Results 91 to 100 of about 29,392,562 (280)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Psychometric properties of the persian version of the nursing clinical reasoning scale

Nursing Open
Aim The aim of this study was to translate the Nursing Clinical Reasoning Scale (NCRS) into Persian and evaluate its psychometric properties. Design This study was a methodological and cross‐sectional study.
Touba Hosseinzadeh, Nastaran Mirfarhadi, Moluk Pouralizadeh, Kian Norouzi Tabrizi, Masoud Fallahi‐Khoshknab, Hamid reza Khankeh, Forozan Shokooh   +6 more
doaj   +1 more source

Bayesian Statistical Inference for Factor Analysis Models with Clustered Data

Mathematics
Clustered data are a complex and frequently used type of data. Traditional factor analysis methods are effective for non-clustered data, but they do not adequately capture correlations between multiple observed individuals or variables in clustered data.
Bowen Chen, Na He, Xingping Li
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Investigating the Factor Structure and Psychometric Properties of the Iranian Version of the Acceptance of Cosmetic Surgery Scale

Journal of Holistic Nursing and Midwifery, 2017
Introduction: Plastic surgery and its acceptance have been increasing in recent years. People have different psychological problems. In recent years, studies have emerged on this group of people.
Zobeydeh Dehghan Manshadi, Mohammad Bagher Kajbaf, Susan Hamedi, Marieh Dehghan Manshadi, Safoora Nowroozi   +4 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Other title: Office of Criminal Justice Services research brief; Other title: Bulletin of the Ohio Statistical Analysis Center

, 2012
Irregular; Began with: Volume 1, Issue 1 (April 2012).; Subtitle varies: "Quarterly bulletin of the Ohio Statistical Analysis Center," April 2012; "A bulletin of the Ohio Statistical Analysis Center," September 2012-; Harvested from the web on 1/6 ...
Ohio Statistical Analysis Center,
core  

Statistical analysis of hydroclimatic time series: Uncertainty and insights

, 2007
Today, hydrologic research and modeling depends largely on climatological inputs, whose physical and statistical behavior are the subject of many debates in the scientific community. A relevant ongoing discussion is focused on long-term persistence (LTP),
Demetris Koutsoyiannis, Alberto Montanari, Koutsoyiannis D, Koutsoyiannis, D, Montanari, A, MONTANARI, ALBERTO   +5 more
core   +1 more source

A Confirmatory Factor Analysis of the Structure of Statistics Anxiety Measure: An examination of four alternative models.

Iranian Journal of Psychiatry, 2011
Objective: The aim of this study is to explore the confirmatory factor analysis results of the Persian adaptation of Statistics Anxiety Measure (SAM), proposed by Earp.
Farahman Farrokhi, Hossein Bevrani
doaj