Results 201 to 210 of about 4,268,227 (240)
R1205H (Vicenza) causes conformational changes in the von Willebrand factor D'D3 domains and enhances von Willebrand factor binding to clearance receptors LRP1 and SR-AI. [PDF]
J Thromb HaemostAtiq F +14 more
europepmc +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
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Immunological Reviews, 2022
SummaryComplement factor D (FD) is a serine protease that plays an essential role in the activation of the alternative pathway (AP) by cleaving complement factor B (FB) and generating the C3 convertases C3(H2O)Bb and C3bBb. FD is produced mainly from adipose tissue and circulates in an activated form.
Hideharu Sekine +2 more
openaire +2 more sources
SummaryComplement factor D (FD) is a serine protease that plays an essential role in the activation of the alternative pathway (AP) by cleaving complement factor B (FB) and generating the C3 convertases C3(H2O)Bb and C3bBb. FD is produced mainly from adipose tissue and circulates in an activated form.
Hideharu Sekine +2 more
openaire +2 more sources
Proceedings of the 12th ACM SIGMETRICS/PERFORMANCE joint international conference on Measurement and Modeling of Computer Systems, 2012
Scheduling multiple jobs onto a platform enhances system utilization by sharing resources. The benefits from higher resource utilization include reduced cost to construct, operate, and maintain a system, which often include energy consumption.
Seung-Hwan Lim +4 more
openaire +1 more source
Scheduling multiple jobs onto a platform enhances system utilization by sharing resources. The benefits from higher resource utilization include reduced cost to construct, operate, and maintain a system, which often include energy consumption.
Seung-Hwan Lim +4 more
openaire +1 more source
ICASSP '82. IEEE International Conference on Acoustics, Speech, and Signal Processing, 2005
For a 2-D wide sense stationary process, the Prediction Theory is revisited and a spectral factorization procedure is obtained via 1-D factorizations.
Hayri Korezlioglu, Philippe Loubaton
openaire +1 more source
For a 2-D wide sense stationary process, the Prediction Theory is revisited and a spectral factorization procedure is obtained via 1-D factorizations.
Hayri Korezlioglu, Philippe Loubaton
openaire +1 more source
Nature, 1951
RICKETS, attended by a reduction in gain of weight, has been frequently reported in weaned lambs grazing on green oat plants and other green feeds during the winter in the South Island of New Zealand1,2. The effect is not confined to green feeds grown in this country, since Ewer has demonstrated a rachitogenic effect of green oats grown in England3.
openaire +2 more sources
RICKETS, attended by a reduction in gain of weight, has been frequently reported in weaned lambs grazing on green oat plants and other green feeds during the winter in the South Island of New Zealand1,2. The effect is not confined to green feeds grown in this country, since Ewer has demonstrated a rachitogenic effect of green oats grown in England3.
openaire +2 more sources