Results 91 to 100 of about 28,757,677 (326)

Impact of Constant Rate Factor on Objective Video Quality Assessment

Advances in Electrical and Electronic Engineering, 2017
This paper deals with the impact of constant rate factor value on the objective video quality assessment using PSNR and SSIM metrics. Compression efficiency of H.264 and H.265 codecs defined by different Constant rate factor (CRF) values was tested.
Juraj Bienik, Miroslav Uhrina, Peter Kortis   +2 more
doaj   +1 more source

Properdin and Factor H: Opposing Players on the Alternative Complement Pathway “See-Saw”

Frontiers in Immunology, 2013
Properdin and factor H are two key regulatory proteins having opposite functions in the alternative complement pathway. Properdin up-regulates the alternative pathway by stabilizing the C3bBb complex, whereas factor H downregulates the pathway by ...
Lubna Kouser, Munirah Abdul-Aziz, Annapurna Nayak, C. Stover, Robert B Sim, U. Kishore   +5 more
semanticscholar   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Zinc-induced Self-association of Complement C3b and Factor H

Journal of Biological Chemistry, 2013
Background: Sub-retinal pigment epithelial deposits contain complement proteins and bioavailable zinc. Results: Ultracentrifugation and x-ray scattering show that >100 μm zinc induces oligomer formation in each of C3, C3u, and C3b, in analogy to Factor H.
R. Nan, Stuart J. Tetchner, E. Rodriguez, P. Pao, J. Gor, I. Lengyel, S. Perkins   +6 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Minimal H-factors and covers

Journal of Applied Probability
AbstractGiven a fixed small graph H and a larger graph G, an H-factor is a collection of vertex-disjoint subgraphs $H'\subset G$, each isomorphic to H, that cover the vertices of G. If G is the complete graph $K_n$ equipped with independent U(0,1) edge weights, what is the lowest total weight of an H-factor?
Joel Larsson Danielsson, Lorenzo Federico   +1 more
openaire   +2 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Discussion: “Stress-Concentration Factors in Shafts With Transverse Holes as Found by Electroplating Method” (Ōkubo, H., and Sato, S., 1955, ASME J. Appl. Mech., 22, pp. 193–196) [PDF]

, 1956
M. M. Leven
openalex   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source