Results 121 to 130 of about 36,394,742 (371)
Impact of Constant Rate Factor on Objective Video Quality Assessment
Advances in Electrical and Electronic Engineering, 2017 This paper deals with the impact of constant rate factor value on the objective video quality assessment using PSNR and SSIM metrics. Compression efficiency of H.264 and H.265 codecs defined by different Constant rate factor (CRF) values was tested.
Juraj Bienik +2 more
doaj +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
FEBS Letters, EarlyView.TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Discussion: “Stress-Concentration Factors in Shafts With Transverse Holes as Found by Electroplating Method” (Ōkubo, H., and Sato, S., 1955, ASME J. Appl. Mech., 22, pp. 193–196) [PDF]
, 1956 M. M. Leven
openalex +1 more source
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Journal of Applied ProbabilityAbstractGiven a fixed small graph H and a larger graph G, an H-factor is a collection of vertex-disjoint subgraphs $H'\subset G$, each isomorphic to H, that cover the vertices of G. If G is the complete graph $K_n$ equipped with independent U(0,1) edge weights, what is the lowest total weight of an H-factor?
Joel Larsson Danielsson +1 more
openaire +2 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Factor H: A Complement Regulator in Health and Disease, and a Mediator of Cellular Interactions
Biomolecules, 2012 Complement is an essential part of innate immunity as it participates in host defense against infections, disposal of cellular debris and apoptotic cells, inflammatory processes and modulation of adaptive immune responses.
Anne Kopp +3 more
semanticscholar +1 more source
Corrigendum: A Family Affair: Addressing the Challenges of Factor H and the Related Proteins
Frontiers in Immunology, 2022 Felix Poppelaars +11 more
doaj +1 more source