In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Identification of a Kingella kingae factor H binding protein that is the major determinant of serum resistance. [PDF]
Hernandez KA +3 more
europepmc +1 more source
THE CO-TO-H2CONVERSION FACTOR FROM INFRARED DUST EMISSION ACROSS THE LOCAL GROUP [PDF]
Adam K. Leroy +10 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Differential modulation of SARS-CoV-2 infection by complement factor H and properdin. [PDF]
Kishore U +12 more
europepmc +1 more source
Interleukin-10 Modifies the Effects of Interleukin-1β and Tumor Necrosis Factor-α on the Activity and Expression of Prostaglandin H Synthase-2 and the NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase in Cultured Term Human Villous Trophoblast and Chorion Trophoblast Cells1 [PDF]
Francesco Pomini +2 more
openalex +1 more source
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Factor H: a novel modulator in sickle cell disease
Wassim El Nemer, Bérengère Koehl
doaj +1 more source
Disease Progression in Age-Related Macular Degeneration Patients Carrying Rare Variants in the Complement Factor H or Complement Factor I Genes. [PDF]
Cinque F +12 more
europepmc +1 more source

