Results 221 to 230 of about 11,250,106 (333)

Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance. [PDF]

Front Immunol
Rodríguez de Córdoba S, Reparaz A, Sanchez D, Pinto S, Juana Lopez L, Martin Merinero H, Calvete I, Perez-Perez J, Jellison SS, Zhang Y, Smith RJH, Moreno I, Dominguez M.   +12 more
europepmc   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Praziquantel and factor H recruitment differentially affect the susceptibility of Schistosoma mansoni to complement-mediated damage. [PDF]

Front Immunol
van Beek AE, Jeanguenat H, Häberli C, Pouw RB, Lamers C, Pál G, Gál P, Schmidt CQ, Ricklin D, Keiser J.   +9 more
europepmc   +1 more source

Human complement factor H [PDF]

, 1991
Wilhelm Schwaeble, Helga Schwaiger, Ricardo A. Brooimans, Antonia Barbieri, Johannes Möst, Monica Hirsch‐Kauffmann, Martin Tiefenthaler, David F. Lappin, Mohamed R. Daha, K Whaley, Manfred P. Dierich   +10 more
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Role of factor H-related protein 3 in Pseudomonas aeruginosa bloodstream infections. [PDF]

Front Immunol
González-Alsina A, Martín-Merinero H, Mateu-Borrás M, Verd M, Doménech-Sánchez A, Goldberg JB, Rodríguez de Córdoba S, Albertí S.   +7 more
europepmc   +1 more source

The Na+/H+ exchanger is constitutively activated in P19 embryonal carcinoma cells, but not in a differentiated derivative. Responsiveness to growth factors and other stimuli.

, 1987
A. J. Bierman, Leon G.J. Tertoolen, Siegfried W. de Laat, Wouter H. Moolenaar   +3 more
openalex   +1 more source

Genetic polymorphism of human factor H (HF,β1H globulin) in Chinese han population in northeast China [PDF]

, 1992
Shigeyuki Tsunenari, Tomoko Higashi, Kazuhiko Kibayashi, Hao Pang, Mei Ding, Jing-Tao Jia   +5 more
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Factor H-related protein 1 in systemic lupus erythematosus. [PDF]

Front Immunol
Kleer JS, Klehr J, Dubler D, Infanti L, Chizzolini C, Huynh-Do U, Ribi C, Trendelenburg M.   +7 more
europepmc   +1 more source