Results 221 to 230 of about 28,757,677 (326)

The Na+/H+ exchanger is constitutively activated in P19 embryonal carcinoma cells, but not in a differentiated derivative. Responsiveness to growth factors and other stimuli.

, 1987
A. J. Bierman, Leon G.J. Tertoolen, Siegfried W. de Laat, Wouter H. Moolenaar   +3 more
openalex   +1 more source

Genetic polymorphism of human factor H (HF,β1H globulin) in Chinese han population in northeast China [PDF]

, 1992
Shigeyuki Tsunenari, Tomoko Higashi, Kazuhiko Kibayashi, Hao Pang, Mei Ding, Jing-Tao Jia   +5 more
openalex   +1 more source

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

Proceedings of the National Academy of Sciences of the United States of America, 2013
E. Malito, A. Faleri, P. Lo Surdo, D. Veggi, Giulietta Maruggi, E. Grassi, E. Cartocci, Isabella Bertoldi, A. Genovese, L. Santini, G. Romagnoli, E. Borgogni, S. Brier, C. Lo Passo, M. Domina, F. Castellino, F. Felici, Stijn van der Veen, Steven Johnson, S. Lea, C. Tang, M. Pizza, S. Savino, N. Norais, R. Rappuoli, M. Bottomley, V. Masignani   +26 more
semanticscholar   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Cytotoxic activity of tumor necrosis factor is inhibited by amiloride derivatives without involvement of the Na⁺/H⁺ antiporter [PDF]

, 1990
Bart Vanhaesebroeck, E. J. Cragoe, Jacques Pouysségur, Rudi Beyaert, Frans van Roy, Walter Fiers   +5 more
openalex   +1 more source

Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.

Journal of the American Society of Nephrology, 2013
Allison M. Lesher, Lin Zhou, Yuko Kimura, Sayaka Sato, Damodar Gullipalli, A. Herbert, P. Barlow, H. Eberhardt, C. Skerka, P. Zipfel, T. Hamano, T. Miwa, K. Tung, W. Song   +13 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Corrigendum: High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3*B

Frontiers in Immunology, 2020
Richard B. Pouw, Richard B. Pouw, Irene Gómez Delgado, Alberto López Lera, Santiago Rodríguez de Córdoba, Diana Wouters, Taco W. Kuijpers, Taco W. Kuijpers, Pilar Sánchez-Corral   +8 more
doaj   +1 more source

Effective long-term treatment with moss-produced factor H by overcoming the antibody response in a mouse model of C3G. [PDF]

Front Immunol
Tschongov T, Konwar S, Kleindienst J, Dabrowska-Schlepp P, Busch A, Schaaf A, Schell C, Rogg M, Häffner K.   +8 more
europepmc   +1 more source