Results 211 to 220 of about 3,730,271 (242)

Factor H binding protein (FHbp): An evaluation of genotypic diversity across Neisseria meningitidis serogroups. [PDF]

Hum Vaccin Immunother
Li Z, Murthy AK, Hao L, Andrew L, Anderson AS.   +4 more
europepmc   +1 more source

Common Haplotypes within the Chromosome 1q31.3 Region Determine Systemic Concentrations of the Entire Complement Factor H Protein Family. [PDF]

J Innate Immun
Veuskens BRJ, van Rossum M, Cattenstart E, Brouwer MC, van Mierlo G, Geissler J, van Leeuwen K, Liu J, Anstadt RA, Richards BT, Hageman GS, Kuijpers TW, Toonen EJM, Pouw RB.   +13 more
europepmc   +1 more source

Low Levels of Complement Factor H in the First Trimester of Pregnancy Are Associated with Spontaneous Preterm Birth. [PDF]

Int J Mol Sci
Becerra-Mojica CH, Mora-Guevara E, Parra-Saavedra MA, Martínez-Vega RA, Díaz-Martínez LA, Rincón-Orozco B.   +5 more
europepmc   +1 more source

Lipid-lowering drug and complement factor H genotyping-personalized treatment strategy for age-related macular degeneration. [PDF]

iScience
Xue CC, Teo KYC, Tham YC, Li H, Thakur S, Sabanayagam C, Fan Q, Silver DL, Wang X, Cheung CMG, Wong TY, Chakravarthy U, Cheng CY, Nusinovici S.   +13 more
europepmc   +1 more source

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Factor H

1990
While the mouse and human H proteins are structurally and functionally similar, they differ in their genetics. Whereas there is no evidence in humans for more than one gene; in mice the H locus is complex. Based on cDNA sequence and hybridization analysis of genomic cosmid clones, there are at least three distinct genes, all highly related to one ...
D P, Vik, P, Muñoz-Cánoves, D D, Chaplin, B F, Tack   +3 more
openaire   +2 more sources

The factor H protein family

Immunopharmacology, 1999
The factor H gene family provides a prime example of a multidomain multifunctional protein family whose individual members are defined by conserved common structural elements and display diverse but often overlapping functions. The six identified members of this protein family represent secreted plasma proteins that are primarily synthesized in the ...
P F, Zipfel, T S, Jokiranta, J, Hellwage, V, Koistinen, S, Meri   +4 more
openaire   +2 more sources

Threshold Functions for H-factors

Combinatorics, Probability and Computing, 1993
Let H be a graph on h vertices, and G be a graph on n vertices. An H-factor of G is a spanning subgraph of G consisting of n/h vertex disjoint copies of H. The fractional arboricity of H is , where the maximum is taken over all subgraphs (V′, E′) of H with |V′| > 1. Let δ(H) denote the minimum degree of a vertex of H. It is shown that if δ(H) < a(
Noga Alon, Raphael Yuster
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Factor H-Related Proteins

2013
Factor H-related proteins (CFHRs) are plasma glycoproteins related in structure and antigenicity to each other and to the complement inhibitory protein factor H. Such proteins are found in most mammals but their number and domain composition vary. This chapter summarizes our current knowledge on the human factor H-related proteins.
Józsi, Mihály, Meri, Seppo
openaire   +2 more sources

Functional Anatomy of Complement Factor H

Biochemistry, 2013
Factor H (FH) is a soluble regulator of the proteolytic cascade at the core of the evolutionarily ancient vertebrate complement system. Although FH consists of a single chain of similar protein modules, it has a demanding job description. Its chief role is to prevent complement-mediated injury to healthy host cells and tissues. This entails recognition
Elisavet, Makou, Andrew P, Herbert, Paul N, Barlow   +2 more
openaire   +2 more sources