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Anti-Factor H Autoantibodies Assay
2013Non-Shiga-toxin-associated hemolytic uremic syndrome (atypical HUS) is a rare form of thrombotic microangiopathy which associates hemolytic anemia, thrombocytopenia, and acute renal failure. In 10 % of cases the disease is linked to presence of autoantibodies directed against Factor H (FH), the main plasmatic alternative complement pathway regulatory ...
Marie-Agnès, Dragon-Durey +6 more
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The Pleiotropy of Complement Factor H
JAMA Ophthalmology, 2023Elizabeth J, Rossin, Lucia, Sobrin
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Factor H and the pathogenesis of renal diseases
Pediatric Nephrology, 2000Complement factor H is a potent inhibitor of alternative pathway complement activation. The factor H gene, a member of the regulators of complement activation (RCA) gene cluster, encodes two plasma proteins, one 150 kilodaltons (kDa) and one 43 kDa.
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Complement Factor H: Physiology and Pathophysiology
Seminars in Thrombosis and Hemostasis, 2001The human plasma protein factor H, which is a multifunctional, multidomain protein, acts as a central regulator of the complement system. In addition to its complement regulatory activities, factor H has multiple physiological activities and 1) acts as an extracellular matrix component, 2) binds to cellular receptors of the integrin type, and 3 ...
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Factor H in the Nutrition of Trout
Science, 1928C M, McCay, F C, Bing, W E, Dilley
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A radiation hybrid map of complement factor H and factor H-related genes
Immunogenetics, 1999M A, Díaz-Guillén +2 more
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