Results 41 to 50 of about 11,953,655 (218)

Dengue virus infection induces complement factor H but protein remains cell-associated, with changes intracellularly and in cell surface binding

Exploration of Immunology
Aim: Severe dengue is correlated with a decrease in the circulating complement regulator, factor H (FH) and prior work has shown that dengue virus (DENV) infection induces FH mRNA but not FH protein release.
Joshua G. Dubowsky, Binoy Appukuttan, Evangeline Cowell, Valeria Sanders, David L. Gordon, Jillian M. Carr   +5 more
doaj   +1 more source

Amnion epithelial cells are an effective source of factor H and prevent kidney complement deposition in factor H-deficient mice

Stem Cell Research & Therapy, 2021
Complement factor H (FH) is the main plasma regulator of the alternative pathway of complement. Genetic and acquired abnormalities in FH cause uncontrolled complement activation amplifying, with the consequent accumulation of complement components on the
Federica Casiraghi, Pamela Yossenaidy Rodriguez Ordonez, Nadia Azzollini, Marta Todeschini, Daniela Rottoli, Roberta Donadelli, Roberto Gramignoli, Ariela Benigni, Marina Noris, Giuseppe Remuzzi   +9 more
doaj   +1 more source

Complement factors (H) into thrombosis [PDF]

Blood, 2017
In this issue of Blood, Ueda et al demonstrate that a mutation in factor H (FH) disrupts host cell interactions, leading to dysregulation of complement, systemic thrombotic angiopathy, and hemolytic uremic syndrome ...
openaire   +2 more sources

Semisimple Hopf actions on Weyl algebras [PDF]

, 2014
We study actions of semisimple Hopf algebras H on Weyl algebras A over a field of characteristic zero. We show that the action of H on A must factor through a group algebra; in other words, if H acts inner faithfully on A, then H is cocommutative.
Cuadra, Juan, Etingof, Pavel, Walton, Chelsea   +2 more
core   +1 more source

Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies

Frontiers in Immunology, 2021
Complement dysregulation is characteristic of the renal diseases atypical hemolytic uremic syndrome (aHUS) and complement component 3 glomerulopathy (C3G).
Markus A. Loeven, Marissa L. Maciej-Hulme, Cansu Yanginlar, Melanie C. Hubers, Edwin Kellenbach, Mark de Graaf, Toin H. van Kuppevelt, Jack Wetzels, Ton J. Rabelink, Richard J. H. Smith, Johan van der Vlag   +10 more
doaj   +1 more source

A near-solar metallicity damped Lyman-alpha system toward the BAL quasar Tol 1037-2703 [PDF]

, 2001
We report the detection of a Broad Absorption Line (BAL) outflow in the spectrum of Tol 1037-2703 with three main BALs at 36000, 25300 and 22300~\kms outflow velocities.
Aldrovandi, Bahcall, Bechtold, Becker, Centurión, Cristiani, D'Odorico, de Kool, Dinshaw, Elvis, Espey, Gaskell, Haardt, Hamann, Hamann, Howk, Jakobsen, Lespine, Meyer, P. Petitjean, Petitjean, Petitjean, Petitjean, Péquignot, Péquignot, R. Srianand, Robertson, Roth, Sargent, Savage, Shull, Songaila, Srianand, Srianand, Srianand, Telfer, Ulrich, Viegas, Voit, Welty, Womble   +40 more
core   +3 more sources

1-(4-Chlorophenyl)-3-(2,4-dichlorobenzoyl)thiourea [PDF]

, 2009
The title compound, C14H9Cl3N2OS, has bond lengths and angles which are quite typical for thiourea compounds of this class. The molecule exists in the solid state in its thione form with typical thiourea C=S and C=O bond lengths, as well as shortened C-N
M. Khawar Rauf, Michael Bolte, Amin Badshah, Allen, Baily, Blessing, Khawar Rauf, Khawar Rauf, Khawar Rauf, Khawar Rauf, Koch, Krishnamurthy, Maryanoff, Namgun, Patil, Sheldrick, Spek, Upadlgaya   +17 more
core   +1 more source

Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.

PLoS Genetics, 2011
Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the ...
Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, Jennifer A Kelly, Kenneth M Kaufman, Carl D Langefeld, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda C Marion, Adam Adler, Stuart B Glenn, Marta E Alarcón-Riquelme, BIOLUPUS Network, GENLES Network, Bernardo A Pons-Estel, John B Harley, Sang-Cheol Bae, So-Young Bang, Soo-Kyung Cho, Chaim O Jacob, Timothy J Vyse, Timothy B Niewold, Patrick M Gaffney, Kathy L Moser, Robert P Kimberly, Jeffrey C Edberg, Elizabeth E Brown, Graciela S Alarcon, Michelle A Petri, Rosalind Ramsey-Goldman, Luis M Vilá, John D Reveille, Judith A James, Gary S Gilkeson, Diane L Kamen, Barry I Freedman, Juan-Manuel Anaya, Joan T Merrill, Lindsey A Criswell, R Hal Scofield, Anne M Stevens, Joel M Guthridge, Deh-Ming Chang, Yeong Wook Song, Ji Ah Park, Eun Young Lee, Susan A Boackle, Jennifer M Grossman, Bevra H Hahn, Timothy H J Goodship, Rita M Cantor, Chack-Yung Yu, Nan Shen, Betty P Tsao   +56 more
doaj   +1 more source

H-Factors in Dense Graphs

Journal of Combinatorial Theory, Series B, 1996
The following asymptotic result is proved. For every \(\varepsilon> 0\), and for every positive integer \(h\), there exists an \(n_0= n_0(\varepsilon, h)\) such that for every graph \(H\) with \(h\) vertices and for every \(n> n_0\), any graph \(G\) with \(hn\) vertices and with minimum degree \[ d\geq \Biggl({\chi(H)- 1\over \chi(H)}+ \varepsilon ...
Alon, Noga, Yuster, Raphael
openaire   +1 more source

CLONING OF THE 1.4-kb mRNA SPECIES OF HUMAN COMPLEMENT FACTOR H REVEALS A NOVEL MEMBER OF THE SHORT CONSENSUS REPEAT FAMILY RELATED TO THE CARBOXY TERMINAL OF THE CLASSICAL 150-kDa MOLECULE [PDF]

, 1991
Three factor H mRNA species of 4.3 kb, 1.8 kb, and 1.4 kb are constitutively expressed in human liver. Having previously characterized full-length cDNA clones derived from the 4.3-kb and 1.8-kb factor mRNA, we report here the isolation and eucaryotic ...
Dierich, Manfred P., Estaller, C., Koistinen, V., Schwaeble, W., Weiss, Elisabeth H.   +4 more
core   +2 more sources