Results 61 to 70 of about 12,019,115 (288)

Tuning the Functionality by Splicing: Factor H and Its Alternative Splice Variant FHL-1 Share a Gene but Not All Functions

Frontiers in Immunology, 2020
The alternative pathway regulator Factor H-like protein 1 (FHL-1) is composed of the first 7 N-terminal complement control protein domains of Factor H (FH) and protects host surfaces from uncontrolled complement attack.
Marco Mannes, Arthur Dopler, Markus Huber-Lang, Christoph Q. Schmidt   +3 more
doaj   +1 more source

Factor H deficiency and fibrillary glomerulopathy [PDF]

Nephrology Dialysis Transplantation, 2004
A 12-month-old boy presented to a local hospital with periorbital oedema and microscopic haematuria. He was pale and hypertensive and had low serum complement C3. He was treated for and followed with the diagnosis of acute post-streptococcal glomerulonephritis. The patient’s parents were second-degree relatives of each other, but his family history was
Solakoglu, S, Bircan, Z, Toprak, D, Turker, G, Kilicaslan, I, Ponard, D, Uysal, V   +6 more
openaire   +3 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs [PDF]

, 2017
Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists.
A Clauss, A Gatt, A Tripodi, A Zambruni, AF Riddell, AO Spiel, B Agarwal, B Agarwal, B Agarwal, DJ Antoine, DJ Antoine, E Gehrie, EA Sankey, FB Mayr, GC Hugenholtz, H Schochl, HJ Tsai, J Vaquero, JG O’Grady, JH Griffin, KC Lee, KC Lee, L Rinaldi, LA Baker, M Habib, M Senzolo, M Yamaguchi, MJ McPhail, P Chowdary, R Jalan, R Kanel von, RT Stravitz, RT Stravitz, SJ Deventer van, SJ Munoz, SR Ostrowski, T Lisman, T Lisman, TE Warkentin, V Rewari   +39 more
core   +4 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Zgamma Production in pbarp Collisions at sqrt(s)=1.8 TeV and Limits on Anomalous ZZgamma and Zgammagamma Couplings

, 1988
We present a study of Z +gamma + X production in p-bar p collisions at sqrt{S}=1.8 TeV from 97 (87) pb^{-1} of data collected in the eegamma (mumugamma) decay channel with the D0 detector at Fermilab.
Abbott, B, Abolins, M, Acharya, BS, Adam, I, Adams, DL, Adams, M, Ahn, S, Aihara, H, Alves, GA, Amidi, E, Amos, N, Anderson, EW, Astur, R, Baarmand, MM, Baden, A, Balamurali, V, Balderston, J, Baldin, B, Banerjee, S, Bantly, J, Barberis, E, Bartlett, JF, Bazizi, K, Belyaev, A, Beri, SB, Bertram, I, Bezzubov, VA, Bhat, PC, Bhatnagar, V, Bhattacharjee, M, Biswas, N, Blazey, G, Blessing, S, Bloom, P, Boehnlein, A, Bojko, NI, Borcherding, F, Boswell, C, Brandt, A, Brock, R, Bross, A, Buchholz, D, Burtovoi, VS, Butler, JM, Carvalho, W, Casey, D, Casilum, Z, Castilla-Valdez, H, Chakraborty, D, Chang, SM, Chekulaev, SV, Chen, LP, Chen, W, Choi, S, Chopra, S, Choudhary, BC, Christenson, JH, Chung, M, Claes, D, Clark, AR, Cobau, WG, Cochran, J, Cooper, WE, Cretsinger, C, Cullen-Vidal, D, Cummings, MAC, Cutts, D, da Motta, H, Dahl, OI, Davis, K, De, K, Del Signore, K, Demarteau, M, Denisov, D, Denisov, SP, Di Loreto, G, Diehl, HT, Diesburg, H, Draper, P, Ducros, Y, Dudko, LV, Dugad, SR, Edmunds, D, Ellison, J, Elvira, VD, Engelmann, R, Eno, S, Eppley, G, Ermolov, P, Eroshin, OV, Evdokimov, VN, Fahland, T, Fatyga, M, Fatyga, MK, Feher, S, Fein, D, Ferbel, T, Finocchiaro, G, Fisk, HE, Fisyak, Y, Flattum, E, Forden, GE, Fortner, M, Frame, KC, Fuess, S, Gallas, E, Galyaev, AN, Gartung, P, Geld, TL, Genik, RJ, Genser, K, Gerber, CE, Gibbard, B, Glenn, S, Gobbi, B, Goforth, M, Goldschmidt, A, Gomez, B, Gomez, G, Goncharov, PI, Gordon, H, Goss, LT, Gounder, K, Goussiou, A, Graf, N, Grannis, PD, Green, DR, Green, J, Greenlee, H, Grim, G, Grinstein, S, Grossman, N, Grudberg, P, Grunendahl, S, Guglielmo, G, Guida, JA, Guida, JM, Gupta, A, Gurzhiev, SN, Gutierrez, P, Gutnikov, YE, Hadley, NJ, Haggerty, H, Hagopian, S, Hagopian, V, Hahn, KS, Hall, RE, Hanlet, P, Hansen, S, Hauptman, JM, Hedin, D, Heinson, AP, Heintz, U, Hernandez-Montoya, R, Heuring, T, Hirosky, R, Hobbs, JD, Hoeneisen, B, Hoftun, JS, Hsieh, F, Hu, T, Hu, T, Huehn, T, Ito, AS, James, E, Jaques, J, Jerger, SA, Jesik, R, Jiang, JZY, Joffe-Minor, T, Johns, K, Johnson, M, Jonckheere, A, Jones, M, Jostlein, H, Jun, SY, Jung, CK, Kahn, S, Kalbfleisch, G, Kang, JS, Karmgard, D, Kehoe, R, Kelly, ML, Kim, CL, Kim, SK, Klatchko, A, Klima, B, Klopfenstein, C, Klyukhin, VI, Kochetkov, VI, Kohli, JM, Koltick, D, Kostritskiy, AV, Kotcher, J, Kotwal, AV, Kourlas, J, Kozelov, AV, Kozlovski, EA, Krane, J, Krishnaswamy, MR, Krzywdzinski, S, Kunori, S, Lami, S, Lan, H, Lander, R, Landry, F, Landsberg, G, Lauer, B, Leflat, A, Li, H, Li, J, Li-Demarteau, QZ, Lima, JGR, Lincoln, D, Linn, SL, Linnemann, J, Lipton, R, Liu, YC, Lobkowicz, F, Loken, SC, Lokos, S, Lueking, L, Lyon, AL, Maciel, AKA, Madaras, RJ, Madden, R, Magana-Mendoza, L, Mani, S, Mao, HS, Markeloff, R, Marshall, T, Martin, MI, Mauritz, KM, May, B, Mayorov, AA, McCarthy, R, McDonald, J, McKibben, T, McKinley, J, McMahon, T, Melanson, HL, Merkin, M, Merritt, KW, Miettinen, H, Mincer, A, Mishra, CS, Mokhov, N, Mondal, NK, Montgomery, HE, Mooney, P, Murphy, C, Nang, F, Narain, M, Narasimham, VS, Narayanan, A, Neal, HA, Negret, JP, Nemethy, P, Norman, D, Oesch, L, Oguri, V, Oltman, E, Oshima, N, Owen, D, Padley, P, Pang, M, Para, A, Park, YM, Partridge, R, Parua, N, Paterno, M, Pawlik, B, Perkins, J, Peters, M, Piegaia, R, Piekarz, H, Pischalnikov, Y, Podstavkov, VM, Pope, BG, Prosper, HB, Protopopescu, S, Qian, J, Quintas, PZ, Raja, R, Rajagopalan, S, Ramirez, O, Rasmussen, L, Reucroft, S, Rijssenbeek, M, Rockwell, T, Roe, NA, Rubinov, P, Ruchti, R, Rutherfoord, J, Sanchez-Hernandez, A, Santoro, A, Sawyer, L, Schaffer, C, Schamberger, RD, Schellman, H, Sculli, J, Shabalina, E, Shankar, HC, Shivpuri, RK, Shupe, M, Singh, H, Singh, JB, Sirotenko, V, Smart, W, Smith, RP, Snihur, R, Snow, GR, Snow, J, Snyder, S, Solis, JLG, Solomon, J, Sood, PM, Sosebee, M, Sotnikova, N, Souza, M, Spadafora, AL, Stephens, RW, Stevenson, ML, Stewart, D, Stichelbaut, F, Stoianova, DA, Stoker, D, Strauss, M, Streets, K, Strovink, M, Sznajder, A, Tamburello, P, Tarazi, J, Tartaglia, M, Thomas, TLT, Thompson, J, Trippe, TG, Tuts, PM, Varelas, N, Varnes, EW, Vititoe, D, Volkov, AA, Vorobiev, AP, Wahl, HD, Wang, G, Warchol, J, Watts, G, Wayne, M, Weerts, H, White, A, White, JT, Wightman, JA, Willis, S, Wimpenny, SJ, Wirjawan, JVD, Womersley, J, Won, E, Wood, DR, Xu, H, Yamada, R, Yamin, P, Yang, J, Yasuda, T, Yepes, P, Yoshikawa, C, Youssef, S, Yu, J, Yu, Y, Zhu, ZH, Zieminska, D, Zieminski, A, Zverev, EG, Zylberstejn, A   +372 more
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Vortex states in superconductors with strong Pauli-paramagnetic effect

, 2007
Using the quasiclassical theory, we analyze the vortex structure of strong-paramagnetic superconductors.There, induced paramagnetic moments are accumulated exclusively around the vortex core. We quantitatively evaluate the significant paramagnetic effect
A. I. Larkin, A. P. Ramirez, G. E. Volovik, Kazushige Machida, Masanori Ichioka   +4 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Anti-Factor H Antibody Reactivity in Young Adults Vaccinated with a Meningococcal Serogroup B Vaccine Containing Factor H Binding Protein

mSphere, 2019
Meningococcal serogroup B (MenB) vaccines contain recombinant factor H binding protein (FHbp), which can complex with complement factor H (CFH) and thereby risk eliciting anti-FH autoantibodies.
Kelsey Sharkey, Peter T. Beernink, Joanne M. Langley, Soren Gantt, Caroline Quach, Christina Dold, Qin Liu, Manuel Galvan, Dan M. Granoff   +8 more
doaj   +1 more source