Results 71 to 80 of about 36,394,742 (371)
Journal of the American Society of Nephrology, 2015 Complement activation is common in patients with IgA nephropathy (IgAN) and associated with disease severity. Our recent genome-wide association study of IgAN identified susceptibility loci on 1q32 containing the complement regulatory protein-encoding ...
Li Zhu +12 more
semanticscholar +1 more source
Frontiers in Immunology, 2017 The complement factor H-related (FHR) proteins are hypothesized to fine-tune the regulatory role of complement factor H (FH) in the alternative pathway of the complement system.
Anna E. van Beek +13 more
doaj +1 more source
occumb: An R package for site occupancy modeling of eDNA metabarcoding data
Population Ecology, EarlyView.This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley +1 more source
Coprime Factor Reduction of H-infinity Controllers [PDF]
, 2003 We consider the efficient solution of the coprime factorization based H infinity controller approximation problems by using frequency-weighted balancing related model reduction approaches.
Varga, Andras
core
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Stable LU factorization of H-matrices
Linear Algebra and its Applications, 1988 This paper shows that an appropriate form of Gaussian elimination is applicable to H-matrices. If A is an arbitrary real matrix it is called an M-matrix if \(a_{ij}\leq 0\) for \(i\neq j\) and if all its eigenvalues have non-negative real part. The comparison matrix \({\mathcal M}(A)\equiv m_{ij}\) of any square complex matrix A is defined by \(m_{ii}=|
Dale D. Olesky +2 more
openaire +2 more sources
Allan variance of frequency fluctuations due to momentum exchange and thermomechanical noises [PDF]
, 2007 We investigate the Allan variance of nanoresonators with random rough surfaces under the simultaneous influence of thermomechanical and momentum exchange noises.
George A. Palasantzas, Roukes M. L.
core +3 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Complement factor H-related hybrid protein deregulates complement in dense deposit disease.
Journal of Clinical Investigation, 2014 The renal disorder C3 glomerulopathy with dense deposit disease (C3G-DDD) pattern results from complement dysfunction and primarily affects children and young adults. There is no effective treatment, and patients often progress to end-stage renal failure.
Qiang Chen +11 more
semanticscholar +1 more source
Frontiers in Immunology, 2020 The alternative pathway regulator Factor H-like protein 1 (FHL-1) is composed of the first 7 N-terminal complement control protein domains of Factor H (FH) and protects host surfaces from uncontrolled complement attack.
Marco Mannes +3 more
doaj +1 more source