Results 101 to 110 of about 14,739,736 (367)

A study to determine the prevalence, clinical profile and incidence of formation of inhibitors in patients of hemophilia in north eastern part of India

Journal of Family Medicine and Primary Care, 2019
Introduction: Deficiency of factor VIII (Hemophilia A), factor IX (Hemophilia B) and Von Willebrand's factor are the most frequent coagulation defects.
Sandip Kumar, Sachidanand Sinha, Anju Bharti, Lalit P Meena, Vineeta Gupta, Jyoti Shukla   +5 more
doaj   +1 more source

Elevated hemostasis markers after pneumonia increases one-year risk of all-cause and cardiovascular deaths [PDF]

, 2011
Background: Acceleration of chronic diseases, particularly cardiovascular disease, may increase long-term mortality after community-acquired pneumonia (CAP), but underlying mechanisms are unknown. Persistence of the prothrombotic state that occurs during
A. Murat Kaynar, AM Toschke, CN Serhan, CR Meier, DC Cowper, Derek C. Angus, EA Halm, EB Milbrandt, F Balkwill, FL Brancati, Florian Mayr, GD Lowe, Gina D'Angelo, GT Kinasewitz, GW Waterer, H Putter, I Koivula, J Bordon, J Kasal, J Kelly, JA Kellum, JL Hsu, JL Vincent, John A. Kellum, JU Hedlund, Kaikobad Irani, L Smeeth, Lisa Weissfeld, ME Charlson, MJ Fine, MJ Pencina, MM Doody, MM Levy, MM Samama, NM Sathiakumar, Patricia T. Bozza, PM Ridker, PR Woodhouse, S Yende, S Yende, Sachin Yende, SE Epstein, Tammy Young, TC Clayton, TT Keller, TT Keller, V Kaplan, VF Corrales-Medina, WA Knaus, WB Kannel   +49 more
core   +5 more sources

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

A Sequential Mechanism for Exosite-mediated Factor IX Activation by Factor XIa*

Journal of Biological Chemistry, 2012
Background: Factor XIa proteolytically activates factor IX. Results: XIa cleaves IX after Arg145, forming IXα, and then after Arg180, forming IXaβ. Both reactions require substrate binding to the XIa A3 domain.
Yipeng Geng, I. Verhamme, A. Messer, Mao-fu Sun, Stephen B. Smith, S. Bajaj, D. Gailani   +6 more
semanticscholar   +1 more source

Change in Cognition Following Ischaemic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline can occur following ischaemic stroke. How cognition changes over time and associations with cognitive change are poorly understood. This study aimed to explore these issues over 2 years following ischaemic stroke.
Wenci Yan, Terence Quinn, Alex McConnachie, Niall Broomfield, Yun Wong, David Dickie, Kirsten Forbes, Matthew Walters, Jesse Dawson   +8 more
wiley   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

THE EFFECT OF ADDITIONAL FASILITY FOR STUDY BASED ON ANIMATION TO THE RESULT IN STUDYING AUDIO MIXER SPECIALLY IN AUDIO VIDEO IN SMK PIRI 1 YOGYAKARTA [PDF]

, 2012
This study was done to know the effect of animation media to the result of students studies in Audio Mixer and to know the increasing of the result of the student study in SMK PIRI 1 Yogyakarta specially in the IX class after using the animation media ...
Nunik, Solichatun
core  

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Protein-Engineered Coagulation Factors for Hemophilia Gene Therapy

Molecular Therapy: Methods & Clinical Development, 2019
Hemophilia A (HA) and hemophilia B (HB) are X-linked bleeding disorders due to inheritable deficiencies in either coagulation factor VIII (FVIII) or factor IX (FIX), respectively.
Benjamin J. Samelson-Jones, Valder R. Arruda   +1 more
doaj   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source