Results 101 to 110 of about 14,898,836 (369)
Liver transplantation: Intraoperative changes in coagulation factors in 100 first transplants [PDF]
, 1989 Six intraoperative blood samples were obtained at intervals from each of 100 individuals undergoing their first liver transplants. The patients fell into the following diagnostic categories: postnecrotic cirrhosis 28, primary biliary cirrhosis 20 ...
Awad, SA +7 more
core +1 more source
Coagulation Factor IX for Hemophilia B Therapy
Acta Naturae, 2012 Factor IX is a zymogen enzyme of the blood coagulation cascade. Inherited absence or deficit of the IX functional factor causes bleeding disorder hemophilia B, which requires constant protein replacement therapy.
N. Orlova +3 more
semanticscholar +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
X-Linked Thrombophilia with a Mutant Factor IX (Factor IX Padua)
New England Journal of Medicine, 2009 We report a case of juvenile thrombophilia associated with a substitution of leucine for arginine at position 338 (R338L) in the factor IX gene (factor IX-R338L). The level of the mutant factor IX protein in plasma was normal, but the clotting activity of factor IX from the proband was approximately eight times the normal level.
SIMIONI, PAOLO +9 more
openaire +3 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The high covalence of metal-ligand bonds as stability limiting factor: the case of Rh(IX)O4+ and Rh(IX)NO3 [PDF]
, 2020 Mateusz A. Domański +3 more
openalex +1 more source
THE EFFECT OF ADDITIONAL FASILITY FOR STUDY BASED ON ANIMATION TO THE RESULT IN STUDYING AUDIO MIXER SPECIALLY IN AUDIO VIDEO IN SMK PIRI 1 YOGYAKARTA [PDF]
, 2012 This study was done to know the effect of animation media to the result of students studies in Audio Mixer and to know the increasing of the result of the student study in SMK PIRI 1 Yogyakarta specially in the IX class after using the animation media ...
Nunik, Solichatun
core
A Sequential Mechanism for Exosite-mediated Factor IX Activation by Factor XIa*
Journal of Biological Chemistry, 2012 Background: Factor XIa proteolytically activates factor IX. Results: XIa cleaves IX after Arg145, forming IXα, and then after Arg180, forming IXaβ. Both reactions require substrate binding to the XIa A3 domain.
Yipeng Geng +6 more
semanticscholar +1 more source