Single‐Crystal Castability of CM186LC Nickel‐Based Superalloy
The optimal conditions to obtain single‐crystal (SX) castings of the directional solidification nickel‐based superalloy CM186LC, are investigated. Cylindrical samples are cast via a proprietary SX Bridgman process. The effect of solidification rates (V) ranging from 1 to 10 mm⋅min−1 on the microstructure is explored.
André Baldissera +3 more
wiley +1 more source
Matching-Adjusted Indirect Comparison of Recombinant Factor IX Albumin Fusion Protein Versus Recombinant Factor IX Fc Fusion Protein for Weekly Prophylactic Treatment of Hemophilia B. [PDF]
Guillet B +6 more
europepmc +1 more source
Microscale 3D Printed Pillars and Porous Polymeric Structures: Manufacturability and Micromechanics
This work demonstrates how two‐photon polymerization enables the fabrication of microscale solid and porous structures from IP‐Q, IP‐S, and IP‐PDMS resins. Combining morphological and mechanical characterization, the study provides the first systematic insights into IP‐Q mechanics and reveals how processing parameters affect structure and stiffness ...
Aikaterini Isaakidou +12 more
wiley +1 more source
Field Study and Correlative Studies of Factor IX Variant FIX-R338L in Participants Treated with Fidanacogene Elaparvovec. [PDF]
Pittman DD +10 more
europepmc +1 more source
A machine learning‐driven framework is introduced to optimize 3D‐printable microneedles for enhanced tissue anchoring and reduced insertion damage. The optimized design achieves a 6.0‐fold improvement in pull‐out‐to‐penetration energy ratio over conventional shapes.
Jegyeong Ryu +5 more
wiley +1 more source
PBPK modeling of recombinant factor IX Fc fusion protein (rFIXFc) and rFIX to characterize the binding to type 4 collagen in the extravascular space. [PDF]
Cloesmeijer ME +6 more
europepmc +1 more source
In‐mold electronics (IME) undergo complex thermoforming and over‐molding processes that strain device integrity. This study demonstrates how adapting the amount and placement of structural adhesive to local deformation levels preserves electrical functionality.
Francisco Ituriel Arias‐García +3 more
wiley +1 more source
A novel snake venom C-type lectin-like protein modulates blood coagulation by targeting von Willebrand factor and coagulation factor IX. [PDF]
Zeng FY +5 more
europepmc +1 more source

