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Coagulation factor V

The International Journal of Biochemistry & Cell Biology, 2004
The coagulation cascade involves sequential enzymatic activations of serine protease zymogens that converge on the generation of thrombin. Factor V (FV) takes part in this process as a component of the prothrombinase complex. Besides its role as procoagulant factor, it is also involved in the physiologic anticoagulant pathway, by participating in the ...
S. Duga, R. Asselta, M.L. Tenchini
openaire   +4 more sources

Factor V

The International Journal of Biochemistry & Cell Biology, 1997
Factor V is a single chain glycoprotein that plays an essential role in the regulation of blood coagulation. After initiation of coagulation, factor V is converted into factor Va through limited proteolysis. Factor Va acts as protein cofactor in the prothrombin-activating complex, which is comprised of the serine protease factor Xa, Ca2+ ions and a ...
J, Rosing, G, Tans
openaire   +2 more sources

Factor V Leiden

JAMA
This JAMA Insights explores factor V Leiden, an inherited thrombophilia, and its association with venous and arterial thrombosis, how it affects pregnancy outcomes, and testing.
Karlyn A, Martin, Mary, Cushman
openaire   +2 more sources

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