Results 211 to 220 of about 2,341,716 (244)
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Factor V in an Industrial Population
British Journal of Haematology, 1976Summary. Factor‐V levels have been measured in a random sample of 626 men and 307 women working in a variety of occupations in North West London. The method is an automated one‐stage assay using the same batch of freeze‐dried thromboplastin, all results being expressed in terms of the same freeze‐dried standard plasma; it has been shown that only one ...
M, Brozović +5 more
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Purification and Stabilization of Factor V
Nature, 1963FACTOR V, a coagulation factor in plasma necessary for the conversion of prothrombin to thrombin, was discovered by Owren in 19431. The same type of activity as part of a hypothetic prothrombin complex was independently described by Quick2, who named it ‘labile factor’.
B, BLOMBACK, M, BLOMBACK
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Thrombosis and Haemostasis, 2013
SummaryFactor V Leiden is a procoagulant mutation associated with venous and arterial thrombosis and pregnancy complications. Its high prevalence of 5% in Caucasians suggests that there are evolutionary benefits as well. Carriers are indeed reported to have various advantageous phenotypes related to haemostasis, inflammation and fertility: less acute ...
Thijs E, van Mens +2 more
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SummaryFactor V Leiden is a procoagulant mutation associated with venous and arterial thrombosis and pregnancy complications. Its high prevalence of 5% in Caucasians suggests that there are evolutionary benefits as well. Carriers are indeed reported to have various advantageous phenotypes related to haemostasis, inflammation and fertility: less acute ...
Thijs E, van Mens +2 more
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Factor V inhibitor in thrombosis
American Journal of Hematology, 1993AbstractA 68‐year‐old previously well woman developed sudden onset of limb gangrene in association with liver dysfunction. An immediately acting inhibitor to factor V with some of the features of lupus anticoagulant was demonstrated. The patient required limb amputation within 2 weeks and activity of the anticoagulant seemed to be on the decline 6 ...
A, Kapur, P R, Kelsey, P E, Isaacs
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Observations on a Factor‐V Inhibitor
British Journal of Haematology, 1975Summary. A 67‐year‐old man developed a potent inhibitor of factor V shortly after undergoing blood transfusions and surgery. The inhibitor reacted in a time‐dependent manner with factor V and gave a non‐linear concentration graph. Studies with specific antisera indicated that it contained γ and μ heavy chains and both κ and λ light chains.
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Factor V Leiden and Contraception
Journal of Midwifery & Women's Health, 2004Factor V Leiden is the most common genetic cause of primary and recurrent venous thromboembolism in women. It is an inherited thrombophilia that results from a genetic mutation. A college‐aged woman who presented for care and had a positive family history of venous thrombosis tested positive for Factor V Leiden.
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American Journal of Hematology, 1985
AbstractA 57‐year‐old married Chinese male without a family history of bleeding disorder was presented with severe hemorrhagic tendency and was subsequently found to be suffering from an acquired inhibitor against coagulation factor V. The prolonged prothrombin time and activated partial thromboplastin time could not be corrected by the addition of ...
L L, Chong, Y C, Wong
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AbstractA 57‐year‐old married Chinese male without a family history of bleeding disorder was presented with severe hemorrhagic tendency and was subsequently found to be suffering from an acquired inhibitor against coagulation factor V. The prolonged prothrombin time and activated partial thromboplastin time could not be corrected by the addition of ...
L L, Chong, Y C, Wong
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Platelet factor V to the rescue
Blood, 2010In this issue of Blood, Duckers and colleagues show that residual platelet factor V is sufficient to promote thrombin generation and likely protects against major bleeding in patients with undetectable plasma factor V.
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Nature, 1964
COAGULATION factor V is involved in the production of both extrinsic and intrinsic thromboplastin in the blood. It deteriorates rapidly during blood storage and the one-stage prothrombin time of stored plasma is prolonged because of factor V deficiency. The factor V concentration of test material may be determined by adding dilutions to aged plasma and
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COAGULATION factor V is involved in the production of both extrinsic and intrinsic thromboplastin in the blood. It deteriorates rapidly during blood storage and the one-stage prothrombin time of stored plasma is prolonged because of factor V deficiency. The factor V concentration of test material may be determined by adding dilutions to aged plasma and
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Studies on factor V in animals
Journal of Comparative Pathology, 1967Summary Studies have been made on the effect of storage and temperature on factor V in animals and a method for its assay is described. There was a decrease of the factor with age in oxalated plasma of cattle, horses, sheep, dogs, rabbits and one elephant. This deterioration was very rapid in plasma kept at 37C.
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