Results 231 to 240 of about 10,152,106 (284)

Hereditary Labile Factor (Factor V) Deficiency

JAMA, 1961
Hereditary labile factor (Factor V) deficiency is transmitted as an autosomal recessive. Only individuals who inherit the defective gene from both parents are bleeders. In the family studied, the father is Greek while the mother is Polish. The diagnosis is made by determining the prothrombin time by the one-stage method, which is completely corrected ...
I A, FRIEDMAN, A J, QUICK, F, HIGGINS, C V, HUSSEY, M E, HICKEY   +4 more
openaire   +2 more sources

Factor V Leiden: a disorder of factor V anticoagulant function

Current Opinion in Hematology, 2004
Activated protein C (APC) resistance, which is often associated with the factor V R506Q (FV Leiden) mutation, is a common risk factor for venous thrombosis. Study of the mechanism of APC resistance has revealed that coagulation FV stimulates the APC-catalysed inactivation of FVIIIa, and that this anticoagulant function of FV is impaired in FV Leiden ...
Elisabetta, Castoldi, Jan, Rosing
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Combined Factor V and Factor VIII Deficiency

Seminars in Thrombosis and Hemostasis, 2009
Combined deficiency of factor V (FV) and factor VIII (FVIII) (F5F8D, or FV+FVIII) is a autosomal recessive bleeding disorder caused by mutations in genes encoding two components of the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC-53), that is, lectin mannose binding protein ( LMAN1) and multiple coagulation factor deficiency 2 ...
Marta, Spreafico, Flora, Peyvandi
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Factor V and Combined Factor V and VIII Deficiency

2018
This chapter outlines the pathophysiology, clinical presentation, inheritance and incidence of factor V deficiency and combined factors V and VIII deficiency. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with factor V deficiency or combined factors V and VIII deficiency.
James P. R. Brown, Joanne Douglas
openaire   +1 more source

[13] Factor V

1993
Publisher Summary The proteolytic activation of prothrombin is catalyzed by an enzyme complex composed of the serine protease factor Xa reversibly associated with the cofactor factor Va on membranes containing negatively charged phospholipid in the presence of calcium ions.
Michael Kalafatis, Sriram Krishnaswamy, Matthew D. Rand, Kenneth G. Mann   +3 more
openaire   +1 more source

[21] Factor V

1981
Publisher Summary This chapter constitutes a report on the procedures currently used in this laboratory to isolate unactivated factor V from bovine plasma. In addition, a method using conventional procedures for the partial purification of factor V from human plasma is presented.
Michael E. Nesheim, Jerry A. Katzmann, Paula B. Tracy, Kenneth G. Mann   +3 more
openaire   +1 more source

[12] Factor V

1976
Publisher Summary Factor V is a plasma protein that is necessary for the optimal rate of conversion of prothrombin to thrombin in both the intrinsic and extrinsic system of blood coagulation. The enzyme responsible for the hydrolytic cleavage of prothrombin to thrombin is activated factor X (Xa), which, in addition to factor V, requires phospholipid ...
Robert W. Colman, Robert M. Weinberg
openaire   +1 more source

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Factor V Leiden

Nursing (Ed. española), 2014
openaire   +2 more sources

factor, v.

2023
openaire   +1 more source