Results 91 to 100 of about 41,383 (293)

Simultaneous subacute coronary drug-eluting stent thrombosis in two different vessels of a patient with factor V Leiden mutation

, 2008
We review the case of a 46-year-old man who underwent elective percutaneous coronary intervention and stenting of the left anterior descending artery and right coronary artery with two sirolimus- and paclitaxel-eluting stents. Four days after angioplasty,
Parham Eshtehardi, Eslami, Masoud, Eshtehardi, Parham, Moayed, Davood Akhlagh, Masoud Eslami, Davood Akhlagh Moayed   +5 more
core   +1 more source

An Integrated and Robust Deep Learning Framework for Denoising and Analyzing Single‐Cell Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
Single‐cell Spatial Transcriptomics Analysis and Denoising Engine is introduced as a unified deep learning framework that jointly performs denoising, clustering, and gene prioritization in spatial transcriptomics. By integrating linear and nonlinear representations within a dual‐channel architecture, it improves robustness and accuracy, uncovers ...
Yaxuan Cui, Yang Cui, Ruheng Wang, Xin Zeng, Zheyong Zhu, Ding Yi, Ruihua Guo, Tetsuya Sakurai, Kenta Nakai, Xiucai Ye, Leyi Wei, Yong Chen   +11 more
wiley   +1 more source

FV Leiden mutation and deep venous thrombosis in Vojvodina: A case-control study [PDF]

Journal of Medical Biochemistry, 2011
Between September 2007 and February 2010, the occurrence of symptomatic deep venous thrombosis (DVT) was investigated in a cohort of 79 consecutive patients. A case-control study included 71 healthy controls matched with cases for sex and age.
Salatić Iva, Kiralj Katarina, Mitić Gorana, Veselinović Igor, Vapa Dušan   +4 more
doaj  

Thrombin generation in a woman with heterozygous factor V Leiden and combined oral contraceptives: A case report

Research and Practice in Thrombosis and Haemostasis, 2020
Combined oral contraceptives and factor V Leiden mutation are multiplicative risk factors for venous thromboembolism. However, it remains unknown whether this multiplicative effect is reflected in thrombin generation assays.
Maxime G. Zermatten, Debora Bertaggia Calderara, Alessandro Aliotta, Lorenzo Alberio   +3 more
doaj   +1 more source

Lessons from snake venom: new insights into the structural and functional aspects of factor V and factor X

, 2021
The venom of the Australian snake Pseudonaja textilis contains coagulation factors V (five) and X (ten) which have been adapted to derail the blood clotting system of its prey.
Verhoef, D.
core  

Biallelic Germline Inactivation of HROB Causes Primary Gonadal Insufficiency and is Potentially Associated with Colonic Polyposis Predisposition

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman, Carli M. Tops, Jelmer Legebeke, Ting Yang, Marcos Díaz Gay, Diantha Terlouw, Lisa E. E. L. O. Lashley, Stefan Aretz, Anna K. Sommer, Mariona Terradas, Laura Valle, Richarda M. de Voer, Ludmil B. Alexandrov, Hans Morreau, Tom van Wezel, Maartje Nielsen   +15 more
wiley   +1 more source

Acute mesenteric ischemia in an African American patient with heterozygous factor V Leiden deficiency

Journal of Community Hospital Internal Medicine Perspectives, 2019
It is well documented that factor V Leiden mutation (FVL) is a common hypercoagulable risk factor in the Caucasian population. Patients with homozygous FVL mutation have an increased risk for venous thromboembolism.
Hadiatou Barry, Ali Ghani, David Gary Smith   +2 more
doaj   +1 more source

Factor-V Leiden G1691A and prothrombin G20210A polymorphisms in Sudanese women with preeclampsia, a case -control study

BMC Medical Genetics, 2019
Background Preeclampsia can lead to adverse maternal and perinatal outcomes. There are few studies on the association of preeclampsia with thrombophilia in Africa including Sudan.
Nadir A. Ahmed, Ishag Adam, Salah Eldin G. Elzaki, Hiba A. Awooda, Hamdan Z. Hamdan   +4 more
doaj   +1 more source

Factor v Leiden homozygous genotype and pregnancy outcomes.

, 2009
International audienceOBJECTIVE: To assess the rate of early (first trimester) and late (second and third trimester) fetal loss in women who are factor V Leiden homozygous.
Biron-Andréani, Christine, Gruel, Yves, Delahousse, Bénédicte, Lequerrec, Agnès, Dutrillaux, Fabienne, Polack, Benoit, Saladin-Thiron, Catherine, Boinot, Catherine, Bauters, Anne, Morange, Pierre-Emmanuel, Le Cam-Duchez, Véronique   +10 more
core   +1 more source

Combined effect of factor V Leiden and prothrombin 20210A on the risk of venous thromboembolism - Pooled analysis of 8 case-control studies including 2310 cases and 3204 controls

, 2001
Factor V Leiden and factor II G20210A mutations are two frequent genetic risk factors involved in venous thromboembolism (VTE). The goal of this pooled analysis of 8 case-control studies, comprising a total of 2310 cases and 3204 controls, was to ...
J. Emmerich, A. Hillarp, M. Cattaneo, M. Margaglione, F. Rosendaal, V. Arruda, T. Cumming, V. De Stefano, J. Reny   +8 more
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