Results 91 to 100 of about 986,336 (320)
Advanced Science, EarlyView.The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther +13 more
wiley +1 more source
Angewandte Chemie, EarlyView.Tuning the rate of covalent network formation in hybrid double network hydrogels regulates whether supramolecular filaments retain their low‐nm structures or depletion‐induced supramolecular assembly takes place forming bundles. This kinetic handle programs the mesoscale architecture and toughness of the hydrogels, establishing a link between ...
Mertcan Özel +7 more
wiley +2 more sources
A systemás lupus erythematosus patogenetikai tényezőinak és klinikai aktivitásának kapcsolata = Pathogenetic factors and clinical activity of systemic lupus erythematosus [PDF]
, 2007 1. Anti-SS-A és SS-B antitestek SLE-ben: 200 SLE-s beteget vizsgáltunk, 38,5% volt SS-A és/vagy SS-B antitest pozitív. A pozitívak között gyakoribb volt a bőrmanifestatio és ritkább a vese-, ill. központi idegrendszeri involvatio.
Gergely, Péter +2 more
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Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Advanced Science, EarlyView.Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients. [PDF]
, 2012 BackgroundUpregulation of the matrix metalloproteinases MMP-2 and MMP-9 in various cancers has been associated with worse survival of the patients.MethodsWe assessed MMP-2 and MMP-9 levels in normal colorectal mucosa from colorectal cancer patients in ...
Hardwick, JCH +8 more
core +1 more source
Advanced Science, EarlyView.Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari +3 more
wiley +1 more source
Factor V Leiden Mutation and Neonatal Stroke
Pediatric Neurology Briefs, 1997 Three infants with familial factor V Leiden mutation and neonatal cerebrovascular disorders are reported from the Children’s Hospital of Philadelphia, PA.
J Gordon Millichap
doaj +1 more source
Ethnic differences in the prevalence of inherited thrombophilic polymorphisms in an asymptomatic Australian prenatal population [PDF]
, 2011 Differences in the prevalence of thrombophilias in different ethnic populations have been demonstrated. Because the Australian population includes many different ethnic groups, we sought to assess the effect of ethnicity in our Australian prenatal ...
Borg, Anthony J. +6 more
core +1 more source
Advanced Science, EarlyView.SpaMode introduces a versatile framework for spatial multi‐omics integration across vertical, horizontal, and mosaic scenarios. By disentangling modality‐invariant and variant features through a mixture‐of‐experts mechanism, it adaptively reconfigures spatially heterogeneous signals.
Xubin Zheng +6 more
wiley +1 more source
Chlamydia pneumoniae fertőzés szerepe a makula degeneráció kialakulásában angiográfiával igazolt koszorúérbetegekben = The role of chlamydia pneumoniae infection in the pathogenesis of age-related macular degeneration in patients with proven coronary artery disease [PDF]
, 2007 Célul tűztük ki, hogy megvizsgáljuk: - a Chlamydia pneumoniae fertőzöttség mértékét AMD-ben (age related macular degeneration) szenvedő és koszorúér betegeken. - a cytokinek kiválasztását pathologias human könnymintákban (1.
Czuriga, István +4 more
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