Results 101 to 110 of about 986,336 (320)
Factor V Leiden and Natural Selection [PDF]
Clinical and Applied Thrombosis/Hemostasis, 2011 [No abstract available]
openaire +3 more sources
Advanced Intelligent Discovery, EarlyView.Automated procedural analysis is recognized as one of the major game changers for robotic surgery. Meaning digital analysis needs to replace the manual assessments that set todays standard. Mechanical robotic‐instrument tracking enables the derivation of quantitative kinematic metrics that support behavior‐based workflow segmentation into distinct ...
Kateryna Pirkovets +4 more
wiley +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Advanced Intelligent Discovery, EarlyView.Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
, 2008 血栓性素因とは血栓症を発症しやすい体質のことである。欧米白人種の血栓性素因は、凝固系第五因子の１箇所の変異（Factor V Leiden（R５０６Q））であることが１０年余り前に判明し、欧米白人に対する血栓症対策は急速に進歩した。しかしながら、黒人やアジア人など欧米白人以外の人種では、Factor V Leiden（R５０６Q）を保因している人は皆無であり、これらの人種での血栓性素因の解明がいそがれていた。我々は日本人ならびにアジア人における血栓性素因の解明を目指して研究を行ってきた。その結果 ...
Naotaka HAMASAKI, 濱崎 直孝
core +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman +15 more
wiley +1 more source
Frequency of factor V Leiden (G1691A) and prothrombin (G20210A) polymorphisms in Population of Kerman Province, Iran [PDF]
Journal of Kerman University of Medical Sciences, 2017 Background & Aims:Thromboembolism is an acute cardiovascular disease that ranges from clinically unimportant to massive embolism. Both acquired and hereditary risk factors contribute to the disease.
Nasrollah Saleh-gohari +1 more
doaj
Fator V de Leiden na doença de Legg-Calvé-Perthes Leiden's V-factor in Legg-Calvé-Perthes disease
Acta Ortopédica Brasileira, 2009 Trobofilias hereditárias têm sido implicadas na patogênese da doenca de Legg-Calvé-Perthes. Uma investigação do fator de risco hereditário mais comum para hipercoagulabilidade - a mutação no gene do fator V (fator V de Leiden) - foi conduzida em 20 ...
Lia Lira Olivier Sanders +5 more
doaj +1 more source
FV Leiden mutation and deep venous thrombosis in Vojvodina: A case-control study [PDF]
Journal of Medical Biochemistry, 2011 Between September 2007 and February 2010, the occurrence of symptomatic deep venous thrombosis (DVT) was investigated in a cohort of 79 consecutive patients. A case-control study included 71 healthy controls matched with cases for sex and age.
Salatić Iva +4 more
doaj
Evaluation of risk factors for thrombophilia in patients with cerebral venous thrombosis [PDF]
, 2010 Objective: The increased risk for thrombosis is known as hypercoagulability or thrombophilia. In our study, we aimed to determine the frequency of the identified defects for thrombophilia in patients with central venous thrombosis aged under 50 years and
Funda Ceran +6 more
core