Results 81 to 90 of about 13,721,448 (320)

Factor V Leiden and Thrombotic Complications in Heparin-induced Thrombocytopenia

, 1998
SummaryTo determine whether factor V Leiden is associated with thrombotic events in patients with heparin-induced thrombocytopenia (HIT), we evaluated 165 patients with serologically confirmed HIT for the presence of factor V Leiden and determined the ...
John Kelton, Theodore Warkentin, Gregory Denomme, Danny Lagrotteria, David Lee   +4 more
core   +1 more source

Factor V Leiden and Thromboembolism [PDF]

Circulation, 1998
To the Editor: In an excellent study, Ridker et al1 recently demonstrated that the risk of thrombosis is greatly increased when the factor V Leiden mutation and hyperhomocysteinemia, which alone are only moderate risk factors for thrombosis, occur together.
Michael Walter, Holger Reinecke, Günter Breithardt, Gerd Assmann, Jürgen Heinrich   +4 more
openaire   +1 more source

Hexagonal Boron Nitride on Liquid and Single‐Crystal Copper: Operando X‐Ray and Atomistic Insights into Growth and Interfacial Structure

Advanced Science, EarlyView.
Liquid metal catalysts are widely assumed to promote high‐quality 2D growth. In this work, operando experiments and machine‐learning‐accelerated simulations show that hBN on Cu breaks this graphene‐derived expectation, where molten Cu promotes multilayer/3D growth, but re‐solidified single‐crystal Cu stabilizes monolayer formation.
Nikoo Ghanadan, Valentina Rein, Hao Gao, Egor Bersenev, Thomas Sarrazin, Manmeet Kaur Sodhi, Bárbara Canto, Irina Snigireva, Nicolas Gauthier, Anastasios C. Manikas, Costas Galiotis, Maciej Jankowski, Gilles Renaud, Athanasios Dimoulas, Karsten Reuter, Oleg Konovalov, Hendrik H. Heenen, Irene M.N. Groot   +17 more
wiley   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Factor V Leiden mutation: An added risk in single ventricle palliation

Annals of Pediatric Cardiology, 2012
We present the case report of a child with Factor V Leiden mutation who underwent Fontan procedure. Thromboembolism is a widely recognized complication of the Fontan procedure and its modifications. Factor V Leiden mutation, being a hypercoagulable state,
R Saileela, C Shanthi, Ravi Agarwal, Raghavan Subramanyan, K M Cherian   +4 more
doaj   +1 more source

‘Vergeten’ bandkeramiek. Een Odyssee naar de oudste neolithische bewoning in Nederland

, 2017
Het archeologisch onderzoek in Nederland naar de vroegneolithische Lineaire Bandkeramiek cultuur of LBK (5250-4950 v. Chr.) heeft een lange geschiedenis.
Wijk, drs I.M. van (Archeologisch Onderzoek Leiden), Velde, dr P. van de (Faculteit der Archeologie, Universiteit Leiden), Amkreutz, dr L..W.S.W. (Rijksmuseum van Oudheden)   +2 more
core   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Factor V Leiden Mutation and its Impact on Pregnancy Complications

Acta Medica, 2011
Objective: The aim of this prospective study was to find the association between the factor V Leiden mutation and adverse pregnancy outcomes. Methods: This study is an analysis of a prospective observational study of the frequency of placenta-mediated ...
Ľubica Hammerová, Ján Chabada, Juraj Drobný, Angelika Bátorová   +3 more
doaj   +1 more source

The impact of the Factor V Leiden mutation on pregnancy

, 2000
A resistance to the anticoagulant activity of activated protein C (APC), most frequently due to a point mutation in the Factor V gene (the Leiden mutation), represents the most common genetic cause of thrombophilia, The Leiden mutation has been ...
V. Spina, F. Morini, ALEANDRI, Vincenzo
core   +1 more source