Results 81 to 90 of about 41,383 (293)
Utility of testing for factor V Leiden.
In 1993, Dahlback and colleagues reported that a poor anticoagulant response to activated protein C was associated with the risk of thrombosis1. Subsequently, it appeared clear that the so-called activated protein C resistance is mostly caused by a mutation in the Arg506 cleavage site of activated factor V2–6.
openaire +2 more sources
Factor V Leiden and Natural Selection [PDF]
[No abstract available]
openaire +3 more sources
Factor v Leiden mutation in severe infection and sepsis
In severe infection and sepsis, activation of coagulation frequently occurs, which contributes to the development of multiple organ dysfunction. Factor V Leiden is a relatively common mutation resulting in a mild prohemostatic state and consequently with
Schouten, Marcel +3 more
core +1 more source
CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang +11 more
wiley +1 more source
Automated procedural analysis is recognized as one of the major game changers for robotic surgery. Meaning digital analysis needs to replace the manual assessments that set todays standard. Mechanical robotic‐instrument tracking enables the derivation of quantitative kinematic metrics that support behavior‐based workflow segmentation into distinct ...
Kateryna Pirkovets +4 more
wiley +1 more source
Hyperfibrinogenaemia is associated with systemic arterial and venous thromboembolism and therefore may contribute to placental vascular disease associated with obstetric complications.
Cohen, H. +4 more
core
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
Frequency of factor V Leiden (G1691A) and prothrombin (G20210A) polymorphisms in Population of Kerman Province, Iran [PDF]
Background & Aims:Thromboembolism is an acute cardiovascular disease that ranges from clinically unimportant to massive embolism. Both acquired and hereditary risk factors contribute to the disease.
Nasrollah Saleh-gohari +1 more
doaj
Fator V de Leiden na doença de Legg-Calvé-Perthes Leiden's V-factor in Legg-Calvé-Perthes disease
Trobofilias hereditárias têm sido implicadas na patogênese da doenca de Legg-Calvé-Perthes. Uma investigação do fator de risco hereditário mais comum para hipercoagulabilidade - a mutação no gene do fator V (fator V de Leiden) - foi conduzida em 20 ...
Lia Lira Olivier Sanders +5 more
doaj +1 more source
Objective: To determine whether methylene tetrahydrofolate reductase (MTHFR) C677T mutation, factor II G20210A mutation and factor V Leiden are risk factors for retinal vein occlusion (RVO) in patients under fifty years of age.
CONTI L +7 more
core

