Results 61 to 70 of about 986,336 (320)

Efficacy and Safety of Direct-Acting Oral Anticoagulants Use in Acute Portal Vein Thrombosis Unrelated to Cirrhosis [PDF]

, 2017
In acute portal vein thrombosis (APVT) unrelated to cirrhosis, anticoagulant therapy is classically started with low molecular weight heparin or vitamin K antagonists.
De Gottardi, A., Morais, S., Nery, F., Teixeira-Gomes, M., Valadares, D.   +4 more
core   +3 more sources

Mechanisms of the Factor V Leiden Paradox [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2008
Objective— Carriers of the factor V Leiden mutation (FVL-carriers) have a substantially increased risk of deep venous thrombosis (DVT), whereas the risk of pulmonary embolism (PE) is only mildly increased compared with noncarriers.
van Stralen, K. J., Doggen, C. J. M., Bezemer, I. D., Pomp, E. R., Lisman, T., Rosendaal, F. R.   +5 more
openaire   +4 more sources

Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis

Advanced Science, EarlyView.
This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu, Kexing Li, Yuge Wang, Hongyu Li, Hongyu Zhao   +4 more
wiley   +1 more source

Prevention of thromboembolic events after radical prostatectomy in patients with hereditary thrombophilia due to a factor V Leiden mutation by multidisciplinary coagulation management

Asian Journal of Urology
Objective: To examine the perioperative impact of factor V Leiden mutation on thromboembolic events' risk in radical prostatectomy (RP) patients. With an incidence of about 5%, factor V Leiden mutation is the most common hereditary hypercoagulability ...
Randi M. Pose, Sophie Knipper, Jonas Ekrutt, Mara Kölker, Pierre Tennstedt, Hans Heinzer, Derya Tilki, Florian Langer, Markus Graefen   +8 more
doaj   +1 more source

Association of extraintestinal manifestations of inflammatory bowel disease in a province of western Hungary with disease phenotype: Results of a 25-year follow-up study [PDF]

, 2003
AIM: IBD is a systemic disease associated with a large number of extraintestinal manifestations (EIMs). Our aim was to determine the prevalence of EIMs in a large IBD cohort in Veszprem Province in a 25-year follow-up study.
Balogh, Zsuzsanna, Dávid, Gyula, Kuronya, Pál, Lakatos, László, Lakatos, Péter László, Pandur, Tünde, Tollas, Árpád   +6 more
core   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

Factor V Leiden mutation: An added risk in single ventricle palliation

Annals of Pediatric Cardiology, 2012
We present the case report of a child with Factor V Leiden mutation who underwent Fontan procedure. Thromboembolism is a widely recognized complication of the Fontan procedure and its modifications. Factor V Leiden mutation, being a hypercoagulable state,
R Saileela, C Shanthi, Ravi Agarwal, Raghavan Subramanyan, K M Cherian   +4 more
doaj   +1 more source

Factor V Leiden and prothrombin G20210A among Chilean patients with venous and arterial thrombosis [PDF]

, 2005
Iván Palomo. Departamento de Bioquímica Clínica e Inmunohematología, Facultad de Ciencias de la Salud. Universidad de Talca, Talca, Chile. Casilla 747,Talca, Chile.Factor V Leiden and G20210A mutation of prothrombin gene are two important genetic ...
Alarcon, M., Hidalgo, P., Palomo, I., Pereira, J., Pinochet, C., Poblete, F., Skagerberg, K., Velez, M.T.   +7 more
core  

Testing for inherited thrombophilia does not reduce the recurrence of venous thrombosis\ud [PDF]

, 2008
Background: Inherited thrombophilia is only weakly associated with recurrence in patients with a first venous thrombosis (VT). In spite of this, thrombophilia testing is often performed in these patients. Positive results may influence patient management
Coppens, M., Doggen, C.J.M., Middeldorp, S., Reijnders, J.H., Rosendaal, F.R.   +4 more
core   +2 more sources

Risk of venous thromboembolism and myocardial infarction associated with factor V Leiden and prothrombin mutations and blood type

Canadian Medical Association Journal, 2013
Background: ABO blood type locus has been reported to be an important genetic determinant of venous and arterial thrombosis in genome-wide association studies. We tested the hypothesis that ABO blood type alone and in combination with mutations in factor
B. F. Sode, K. H. Allin, M. Dahl, F. Gyntelberg, B. Nordestgaard   +4 more
semanticscholar   +1 more source