Results 51 to 60 of about 41,383 (293)

Factor V Leiden and Thrombotic Complications in Heparin-induced Thrombocytopenia

open access: yes, 1998
SummaryTo determine whether factor V Leiden is associated with thrombotic events in patients with heparin-induced thrombocytopenia (HIT), we evaluated 165 patients with serologically confirmed HIT for the presence of factor V Leiden and determined the ...
John Kelton   +4 more
core   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study from the EUSTAR Cohort

open access: yesArthritis Care &Research, Accepted Article.
Objective JAK inhibitors (JAKis) have shown promising effects in early‐phase studies of SSc. We aimed to assess the safety and explore effectiveness of JAKis compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the EUSTAR cohort was performed.
Stefano Di Donato   +27 more
wiley   +1 more source

FACTOR V LEIDEN MUTATIONS AND UNILATERAL RETINAL VEIN OCCLISION: A REGIONAL STUDY OF EASTERN PART OF TURKEY

open access: yesEurasian Journal of Medicine, 2019
Purpose: We investigated the role of factor V Leiden mutation in patients with retinal vein occlusion (RVO). Method: Factor V Leiden mutation was investigated in DNA obtained from the peripheral blood of 30 patients, diagnosed with retinal vein ...
Orhan Ateş, Orhan Baykal
doaj  

The Association between Preeclampsia and Defined Polymorphisms in Prothrombin and Coagulation Factor V Genes [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2016
Background & Aims: Preeclampsia is one of the complications of pregnancy and a major cause of maternal mortality. Since, hypercoagulation is one of the risk factors, defined polymorphisms of V and II coagulation factors (G1691A and G20210A) may increase ...
Zohreh Salari   +3 more
doaj  

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

open access: yesAdvanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu   +13 more
wiley   +1 more source

Factor V Leiden mutation: An added risk in single ventricle palliation

open access: yesAnnals of Pediatric Cardiology, 2012
We present the case report of a child with Factor V Leiden mutation who underwent Fontan procedure. Thromboembolism is a widely recognized complication of the Fontan procedure and its modifications. Factor V Leiden mutation, being a hypercoagulable state,
R Saileela   +4 more
doaj   +1 more source

Factor‐V Leiden: a risk factor for cerebral palsy [PDF]

open access: yesDevelopmental Medicine & Child Neurology, 1999
Inherited and acquired thrombophilic disorders have recently been associated with cerebral palsy (CP) and complications in pregnancy. Thrombophilic disorders are not diseases per se, but are recognized risk factors for a variety of diseases across all ages, including atherosclerosis, cerebral infarction, inflammatory bowel disease, Legg–Perthes disease,
K H, Harum, A H, Hoon, J F, Casella
openaire   +2 more sources

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

open access: yesAdvanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth   +10 more
wiley   +1 more source

Prevention of thromboembolic events after radical prostatectomy in patients with hereditary thrombophilia due to a factor V Leiden mutation by multidisciplinary coagulation management

open access: yesAsian Journal of Urology
Objective: To examine the perioperative impact of factor V Leiden mutation on thromboembolic events' risk in radical prostatectomy (RP) patients. With an incidence of about 5%, factor V Leiden mutation is the most common hereditary hypercoagulability ...
Randi M. Pose   +8 more
doaj   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

open access: yesAdvanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu   +5 more
wiley   +1 more source

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