Revista Brasileira de Hematologia e Hemoterapia, 2006 As tromboses são eventos de etiopatogênese multifatorial resultantes da interação de fatores genéticos e ambientais, constituindo na atualidade uma das causas mais comuns de morbimortalidade.
Catarina P. S. Ramos +6 more
doaj +1 more source
Factor V Leiden mutation and pregnancy. Haemostasis during pregnancy in non-carriers and carriers of factor V Leiden mutation, with special emphasis on placenta-mediated and venous thromboembolic complications and on blood coagulation and fibrinolysis markers for prediction of complications [PDF]
, 2009 Factor V Leiden (FVL) mutation elevates the risk of venous thromboembolism (VTE) in general. During pregnancy, the haemostatic balance is changed in the direction of hypercoagulability, resulting in an increased incidence of VTE. 42 women were followed
Kjellberg, Ulla
core +1 more source
Современная ревматология, 2021 The article provides a description of the systemic lupus erythematosus patient with multiple avascular bone necrosis (ABN), homozygous mutation in clotting factor V (Leiden) gene, who successfully underwent the total hip replacement.
F. A. Cheldieva +4 more
doaj +1 more source
Factor V Leiden Mutation - an Unusual Cause of Hypopituitarism?
Endocrinology Research and Practice, 2022 Hypopituitarism is a disorder of diverse etiology that results in partial or total loss of pituitary functions. Here we report a 49-year-old female patient presenting with absence of peripheral pulses of the right upper extremity and anterior pituitary ...
Ekrem Algün +9 more
doaj +2 more sources
Factor V Leiden and venous thrombosis: First case report from Iraq
مجلة كلية الطب, 2005 Background: Factor V Leiden mutation is the most common cause of hereditary thrombophilia . this mutation was found to be highly prevalent in the Eastern Mediterranean region , with recently reported prevalence of 3% in random Iraqi blood donors.
Nasir AL-Allawi +3 more
doaj +1 more source
Haematologica, 2008 Background Routine analyses for thrombophilia include determination of the presence of factor V Leiden and prothrombin 20210A polymorphisms. However, the usefulness of these determinations is controversial and the clinical benefit remains questioned ...
Antonia Miñano +11 more
doaj +1 more source
Evaluation of Genetic and Environmental Risk Factors for Deep Vein Thrombosis in Sudanese [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Thrombophilia is a multi-factorial hypercoagulability disorder. The predisposing factors may be inherited, acquired or both. Factor V Leiden prothrombin 20210G>A mutations are the most common inherited factors.
Nadir Ahmed Ibrahim +3 more
doaj +1 more source
Current evidence for outcomes of free-flap reconstruction in factor V Leiden patients
Australasian Journal of Plastic Surgery, 2019 **Background**: Factor V Leiden is the most common form of inherited thrombophilic syndrome, affecting 5 per cent of Caucasians. While increased rates of venous thromboembolic complications have been regularly reported in factor V Leiden patients, little
Isobel Yeap +4 more
doaj +1 more source
Evaluation the frequency of factor V Leiden mutation in pregnant women with preeclampsia syndrome in an Iranian population [PDF]
Iranian Journal of Reproductive Medicine, 2012 Background: Role of genetic factors in etiology of preeclampsia is not confirmed yet.Objective: Gene defect frequency varies in different geographic areas as well as ethnic groups.
Azadeh Azinfar +4 more
doaj
Prothrombin G20210A and Factor V Leiden mutations in ischemic arterial stroke
Van Tıp Dergisi, 2018 INTRODUCTION: Ischemic stroke remains an important public health problem in all over world. It is wellknown that, some type of genetic mutations such as factor V Leiden and prothrombin G20210A contribute to the risk of ischemic venous stroke.
Hafize Nalan Güneş
doaj +1 more source