Results 21 to 30 of about 41,383 (293)
The prevalence of Factor V Leiden (Arg506Gln) mutation in King Khalid University Hospital patients, 2017–2019 [PDF]
, 2021 Arg506Gln mutation is responsible for one of the procoagulant factors and most common inherited thrombophilia in the Factor V Leiden (FVL) family. The replacement of the missense mutation for Arg506Gln / R506Q is at 1691st position from Guanine to ...
Alotaibi, Abdulaziz A. +10 more
core +1 more source
Mechanisms of the Factor V Leiden Paradox [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2008 Objective— Carriers of the factor V Leiden mutation (FVL-carriers) have a substantially increased risk of deep venous thrombosis (DVT), whereas the risk of pulmonary embolism (PE) is only mildly increased compared with noncarriers.
van Stralen, K. J. +5 more
openaire +4 more sources
Recurrent pregnancy loss: can factor V Leiden mutations be a cause [PDF]
Obstetrics & Gynecology Science, 2019 The role of Factor V Leiden (FVL) mutation in recurrent miscarriages has been disputed. It has been hypothesized that FVL mutation in patients with recurrent miscarriages is treatable.
R R N Reddy +3 more
doaj +1 more source
Современная ревматология, 2021 The article provides a description of the systemic lupus erythematosus patient with multiple avascular bone necrosis (ABN), homozygous mutation in clotting factor V (Leiden) gene, who successfully underwent the total hip replacement.
F. A. Cheldieva +4 more
doaj +1 more source
Is Factor V Leiden a Risk Factor for Fetal Loss?
Acta Medica, 1999 A successful pregnancy is dependent on the development of adequate placental circulation. The abnormalities of placental vasculature may result in a number of gestational pathologies, including fetal loss.
Petr Dulíček +5 more
doaj +1 more source
Evaluation of Genetic and Environmental Risk Factors for Deep Vein Thrombosis in Sudanese [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Thrombophilia is a multi-factorial hypercoagulability disorder. The predisposing factors may be inherited, acquired or both. Factor V Leiden prothrombin 20210G>A mutations are the most common inherited factors.
Nadir Ahmed Ibrahim +3 more
doaj +1 more source
Factor V Leiden thrombophilia [PDF]
Genetics in Medicine, 2011 Factor V Leiden is a genetic disorder characterized by a poor anticoagulant response to activated Protein C and an increased risk for venous thromboembolism. Deep venous thrombosis and pulmonary embolism are the most common manifestations, but thrombosis in unusual locations also occurs.
openaire +2 more sources
Revista Brasileira de Hematologia e Hemoterapia, 2006 As tromboses são eventos de etiopatogênese multifatorial resultantes da interação de fatores genéticos e ambientais, constituindo na atualidade uma das causas mais comuns de morbimortalidade.
Catarina P. S. Ramos +6 more
doaj +1 more source
Prevalence of the factor V Leiden mutation in patients susceptible to venous thromboembolism
, 2020 Background. A tendency to venous thromboembolism is otherwise called hypercoagulability or thrombophilia. This disease can be acquired or have a genetic background, and may lead to pulmonary embolism. The basis for analysis and selection of treatment is
Elżbieta Wierszyło +6 more
core +1 more source
Prevalence and Clinical Significance of Factor V Leiden Mutation in Egyptian Preeclamptic Women [PDF]
International Journal of Medical Arts, 2021 Background: Factor V [Leiden] mutation, also known as activated protein-C resistance, is the most common of the inherited thrombophilias. Aim of the work: The present study aimed to ass the prevalence of factor V Leiden mutation in a group of Egyptian ...
Ahmed Alsheikh +2 more
doaj +1 more source