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A Rare Case of Quadruple Limb Amputation due to Factor V Leiden Mutation
Indian Journal of Physical Medicine & Rehabilitation, 2022 Factor V Leiden, an autosomal dominant gene mutation that leads to increase risk of forming thrombophilia. Amputation in patients with Factor V leiden mutation is known but none describe quad-limb amputation in this setting.
Ann Noble Zachariah, Ravi Sankaran
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Circulation, 2003 You may have been tested for the condition known as factor V Leiden (pronounced factor five lye/-den) because you or someone in your family has had a blood clot in one of the deep veins of the body (also called deep vein thrombosis, or DVT) or a blood clot that traveled to the lung (also called a pulmonary embolism, or PE).
Deborah L. Ornstein, Mary Cushman
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The frequency of factor V G1691A (Leiden) mutation in the healthy Kazakh population [PDF]
Turkish Journal of Hematology, 2011 Hakkı Taştan
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Indian Journal of Pathology and Microbiology, 2020 Background: Thrombophilia is a hypercoagulable state characterized by increased venous thrombosis. The most common cause of heritable thrombophilia is Factor V Leiden (FVR506Q) homozygous state, with a relative risk of 10–80 times as compared to normal ...
Mirza Asif Baig
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Factor V Leiden and Inflammation [PDF]
Thrombosis, 2012 Factor V Leiden, is a variant of human factor V (FV), also known as proaccelerin, which leads to a hypercoagulable state. Along these years, factor V Leiden (FVL) has been studied from the pathophysiologic point of view, and research has been focused on finding clinical approaches for the management of the FVL associated to a trombophilic state.
Silvia Perez-Pujol +2 more
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Frequency of factor II G20210A, factor V Leiden, MTHFR C677T and PAI-1 5G/4G polymorphism in patients with venous thromboembolism: Croatian case-control study [PDF]
, 2010 Introduction: Venous thromboembolic disease is one of the leading causes of morbidity and mortality in the developed world. Identification of hereditary factors of thrombophilia is contributing to a better understanding of the etiology and disease ...
Ana-Maria Simundic +7 more
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Hormonal replacement therapy, prothrombotic mutations and the risk of venous thrombosis [PDF]
, 2002 Hormone replacement therapy (HRT) increases the risk of venous thrombosis. We investigated whether this risk is affected by carriership of hereditary prothrombotic abnormalities.
A. Rumley +26 more
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Recurrent pregnancy loss: can factor V Leiden mutations be a cause [PDF]
Obstetrics & Gynecology Science, 2019 The role of Factor V Leiden (FVL) mutation in recurrent miscarriages has been disputed. It has been hypothesized that FVL mutation in patients with recurrent miscarriages is treatable.
R R N Reddy +3 more
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