Results 161 to 170 of about 38,180 (186)
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Factor V Leiden

Journal of Infusion Nursing, 2009
As one whose family has been affected by factor V Leiden since 1980, the author knows firsthand the impact of this disease process on patients, outcomes, and practice. In today's healthcare environment, genetic screening for the factor V mutation is routine among pregnant women.
Robert J. Desnick   +48 more
openaire   +3 more sources

The Factor V (Leiden) Test [PDF]

open access: yesThrombosis Research, 1999
Introduction: Pre-Eclampsia (PE) is a pregnancy-specific disorder which further complicates and leads to eclampsia. The Factor V Leiden (FVL) is an autosomal dominant genetic abnormality with incomplete penetrance predisposes to thrombosis.
Peter Quehenberger   +4 more
openaire   +2 more sources

Factor V Leiden and hemophilia

Thrombosis Research, 2010
Several inherited prothrombotic risk factors have been identified so far. Among them, the factor V (FV) Leiden mutation causes a reduced ability of activated protein C to inactivate activated FV and is the most frequent genetic predisposing factor for venous thromboembolism.
Franchini M, LIPPI, Giuseppe
openaire   +3 more sources

Evolution of Factor V Leiden

Thrombosis and Haemostasis, 2013
SummaryFactor V Leiden is a procoagulant mutation associated with venous and arterial thrombosis and pregnancy complications. Its high prevalence of 5% in Caucasians suggests that there are evolutionary benefits as well. Carriers are indeed reported to have various advantageous phenotypes related to haemostasis, inflammation and fertility: less acute ...
Thijs E, van Mens   +2 more
openaire   +2 more sources

Factor V Leiden

JAMA
This JAMA Insights explores factor V Leiden, an inherited thrombophilia, and its association with venous and arterial thrombosis, how it affects pregnancy outcomes, and testing.
Karlyn A, Martin, Mary, Cushman
openaire   +2 more sources

Factor V Leiden and Contraception

Journal of Midwifery & Women's Health, 2004
Factor V Leiden is the most common genetic cause of primary and recurrent venous thromboembolism in women. It is an inherited thrombophilia that results from a genetic mutation. A college‐aged woman who presented for care and had a positive family history of venous thrombosis tested positive for Factor V Leiden.
openaire   +2 more sources

Factor V Leiden

Dimensions of Critical Care Nursing, 2010
Venous thromboembolism accounts for approximately 600,000 hospitalizations and 50,000 deaths per year in the United States. Many inherited blood disorders predispose patients to this disorder. The most common of these disorders is factor V Leiden. Factor V Leiden thrombophilia is an inherited disorder, mutation, of the mechanisms of blood clotting. The
openaire   +2 more sources

HELLP syndrome and factor V Leiden

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2001
The association of thrombophilia and obstetrical complications is documented and well consistent with the hypothesis of an insufficient placental perfusion due to fibrin deposition as a major underlying pathophysiological mechanism. Factor V Leiden is one of the most frequent thrombophilic mutations. A high prevalence of this mutation has recently been
M, Bozzo   +6 more
openaire   +2 more sources

World distribution of factor V Leiden

The Lancet, 1995
We have analysed 3380 chromosomes (1690 unrelated individuals) from twenty-four populations for the presence of factor V Leiden, an important risk factor in venous thromboembolism. The allele frequency in 618 Europeans was 4.4%, with the highest prevalence among Greeks (7%). It was 0.6% in Asia Minor.
D C, Rees, M, Cox, J B, Clegg
openaire   +2 more sources

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