Results 11 to 20 of about 77,059 (283)

Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation.

Lancet, The, 1994
J. Vandenbroucke, T. Koster, E. Briet, P. Reitsma, R. Bertina, F. Rosendaal   +5 more
semanticscholar   +3 more sources

Addendum to “on the measurability of a function which occurs in a paper by A. C. Zaanen” [PDF]

, 1963
Current guidelines discourage combined oral contraceptive (COC) use in women with hereditary thrombophilic defects. However, qualifying all hereditary thrombophilic defects as similarly strong risk factors might be questioned. Recent studies indicate the
Buller, Harry R., Hamulyak, Karly, Meijer, Karina, Middeldorp, Saskia, Prins, Martin H., van Vlijmen, Elizabeth F. W., Veeger, Nic J. G. M.   +6 more
core   +13 more sources

A Rare Case of Quadruple Limb Amputation due to Factor V Leiden Mutation

Indian Journal of Physical Medicine & Rehabilitation, 2022
Factor V Leiden, an autosomal dominant gene mutation that leads to increase risk of forming thrombophilia. Amputation in patients with Factor V leiden mutation is known but none describe quad-limb amputation in this setting.
Ann Noble Zachariah, Ravi Sankaran
doaj   +1 more source

Risk of venous thromboembolism in association with factor V leiden in cancer patients - The EDITH case-control study. [PDF]

PLoS ONE, 2018
Cancer and factor V Leiden mutation are both risk factors for venous thromboembolism (VTE). Cancer critically increases the thrombotic risk whereas Factor V Leiden is the most common pro-thrombotic mutation.
Adeline Heraudeau, Aurélien Delluc, Mickaël Le Henaff, Karine Lacut, Christophe Leroyer, Benoit Desrues, Francis Couturaud, Cécile Tromeur   +7 more
doaj   +1 more source

Prevalence and Clinical Significance of Factor V Leiden Mutation in Egyptian Preeclamptic Women [PDF]

International Journal of Medical Arts, 2021
Background: Factor V [Leiden] mutation, also known as activated protein-C resistance, is the most common of the inherited thrombophilias. Aim of the work: The present study aimed to ass the prevalence of factor V Leiden mutation in a group of Egyptian ...
Ahmed Alsheikh, Ahmed Elsadek, Samy Gebreel   +2 more
doaj   +1 more source

Comparative analysis of “APTT vs RVVT” based activated protein C resistance assay in the diagnosis of Factor V Leiden mutation

Indian Journal of Pathology and Microbiology, 2020
Background: Thrombophilia is a hypercoagulable state characterized by increased venous thrombosis. The most common cause of heritable thrombophilia is Factor V Leiden (FVR506Q) homozygous state, with a relative risk of 10–80 times as compared to normal ...
Mirza Asif Baig
doaj   +1 more source

MATERNAL AND FETAL COMPLICATIONS OCCURRING IN HEREDITARY THROMBOPHILIA [PDF]

Romanian Journal of Pediatrics, 2017
Objective. To identify qualitative and quantitative changes involving coagulation factors engaged in maternal and fetal complications, to determine the level of correlation between them, and to highlight the involvement of hereditary thrombophilia among ...
Janina-Georgiana Nacea, Nicolae Cernea, Viorela Enachescu, Loredana Anghel, Constantin Kamal, Ion Cristian Efrem, Ana-Maria Patrascu, Ionela Rotaru   +7 more
doaj   +1 more source

Maternal Factor V Leiden Mutation in Preeclampsia: A Case-Control South Eastern Indian Tertiary Care Hospital Based Study [PDF]

Journal of Clinical and Diagnostic Research, 2020
Introduction: Pre-Eclampsia (PE) is a pregnancy-specific disorder which further complicates and leads to eclampsia. The Factor V Leiden (FVL) is an autosomal dominant genetic abnormality with incomplete penetrance predisposes to thrombosis.
Krishnaveni Changalvala, Pushpa Kotur, Mitesh Shetty, KS Praveen Kumar, TV Jagadish, Sharath Balakrishna, KV Venkateshu   +6 more
doaj   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Avascular necrosis in systemic lupus erythematosus: total hip replacement in a patient with mutation in clotting factor V (Leiden) gene, clinical observation

Современная ревматология, 2021
The article provides a description of the systemic lupus erythematosus patient with multiple avascular bone necrosis (ABN), homozygous mutation in clotting factor V (Leiden) gene, who successfully underwent the total hip replacement.
F. A. Cheldieva, I. G. Kushnareva, V. V. Babak, A. E. Khramov, T. M. Reshetnyak   +4 more
doaj   +1 more source