Results 221 to 230 of about 77,059 (283)

Arterial strokes associated with factor V Leiden mutation

Hospital Medicine, 2001
A 41-year-old Caucasian woman was admitted with right hemiparesis and blurred vision. There was no history of hypertension, diabetes, ischaemic heart disease, previous stroke, oral contraceptive use or miscarriages nor any family history of stroke. She was a non-smoker. Clinical examination confirmed the presence of right-sided weakness. There were no
S K, Munshi, D, Hall, R, Evans, T, Robinson   +3 more
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Factor V Leiden Mutation in Severe Infection and Sepsis

Seminars in Thrombosis and Hemostasis, 2011
In severe infection and sepsis, activation of coagulation frequently occurs, which contributes to the development of multiple organ dysfunction. Factor V Leiden is a relatively common mutation resulting in a mild prohemostatic state and consequently with an increased tendency to develop thrombosis.
Levi, Marcel, Schouten, Marcel, van't Veer, Cees, van der Poll, Tom   +3 more
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Screening for the Factor V Leiden Mutation

2003
Familial clustering of thrombosis suggests that genetic risk factors are important in the pathogenesis of venous thromboembolism. However, until recently, well defined genetic defects such as antithrombin, protein C and protein S deficiencies accounted for less than 10% of patients with thrombosis.
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Role of the factor V Leiden mutation in septic peritonitis assessed in factor V Leiden transgenic mice*

Critical Care Medicine, 2006
The factor V Leiden (FVL) mutation (Arg506Glu) results in the production of an FV protein that when activated is relatively resistant to inactivation by activated protein C and thereby leads to predisposition to thrombosis. The rather high prevalence of the FVL mutation in the general population prompted speculation about a potential survival benefit ...
Brüggemann, Lois W., Schoenmakers, Saskia H. H. F., Groot, Angelique P., Reitsma, Pieter H., Spek, C. Arnold   +4 more
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Discussion: ‘Factor V Leiden mutation’ by Kjellberg et al

American Journal of Obstetrics and Gynecology, 2010
In the roundtable that follows, clinicians discuss a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research.
Isabelle, Wilkins, Gary, Loy, Cecilia, Gambala, Tamika, Alexander, Amy, Cline, Krista, Childress   +5 more
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Factor V Leiden mutation and type 1 diabetes mellitus

Blood Coagulation & Fibrinolysis, 2008
Diabetes mellitus is considered to cause a tendency for arterial thrombosis. Recent studies addressed the association between venous and arterial disease. Resistance to activated protein C is one of the most common causes of venous thrombosis and linked to a single point mutation in the factor V gene, designated as factor V Leiden mutation.
Asli Nar, Demirer, Mehmet, Alikasifoglu, Ergul, Tuncbilek, Sema, Karakus, Tomris, Erbas   +4 more
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Arterial Thrombosis in Mice with Factor V Leiden Mutation

Vascular, 2008
The factor V Leiden (FVL) mutation has been demonstrated to be associated with the development of venous thrombosis in humans. Whether such a propensity also exists in the arterial circulation remains controversial. In an effort to minimize the variability that clouds the clinical study of arterial thrombosis, we studied FVL-associated arterial ...
Ellis S, Sampram, Yasser, Saad, Kenneth, Ouriel   +2 more
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BUDD-CHIARI SYNDROME RELATED TO FACTOR V LEIDEN MUTATION

American Journal of Gastroenterology, 1998
We here describe a young patient who presented with chronic Budd-Chiari syndrome. An exhaustive etiological investigation to detect a procoagulable state was negative except for factor V mutation (factor V Leiden), a factor associated with resistance to activated protein C. Factor V Leiden is known to be a common, high risk factor for thrombosis.
J, Delarive, J J, Gonvers
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Prevalence of Factor V Leiden Mutation in Non-European Populations

Thrombosis and Haemostasis, 1997
SummaryA difference in the prevalence of venous thromboembolism (TE) in major human groups has been described and an uneven distribution of FV Leiden mutation over the world has recently been reported.We investigated FV Leiden mutation in 584 apparently healthy sub#jects mostly from populations different from those previously investi#gated: 170 ...
PEPE, GUGLIELMINA, O. Rickards, O.C. Vanegas, T. Brunelli, GORI, ANNA MARIA, GIUSTI, BETTI, ATTANASIO, MONICA, PRISCO, DOMENICO, GENSINI, GIAN FRANCO, ABBATE, ROSANNA   +9 more
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Factor V Leiden Mutation in Venous Thrombosis in Southeast Turkey

Angiology, 2006
Venous thrombosis (VT) is a common disease, with an annual incidence in the general population of approximately 1 per 1,000. Factor V Leiden mutation (G1691A) (FVL) is the most common risk factor in venous thrombosis. The prevalence of FVL for thrombosis varies greatly in different regions of the world.
Sevgi, Kalkanli, Orhan, Ayyildiz, Naci, Tiftik, Sabri, Batun, Abdurrahman, Isikdogan, Hakan, Ince, Selahaddin, Tekes, Ekrem, Muftuoglu   +7 more
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