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Because of the very short half-life of factor VII, prophylaxis in factor VII deficiency is considered a difficult endeavor. The clinical efficacy and safety of prophylactic regimens, and indications for their use, were evaluated in factor VII-deficient ...
Mariasanta Napolitano +13 more
doaj +2 more sources
Inhibitors to factor
We performed a prospective study of FVII inhibitor occurrence in a large number of patients with FVII deficiency who had received replacement therapy for spontaneous or traumatic bleeding episodes, major or minor surgical interventions or prophylaxis.Inhibitor development was detected in 2.6% (3/115) of patients, but the incidence of de novo inhibitors
Batorova A +11 more
openaire +4 more sources
A 5-year-old Chinese boy with mild symptoms despite severe congenital factor VII deficiency: A case report [PDF]
Congenital factor VII deficiency is a rare autosomal recessive bleeding disorder characterized by markedly heterogeneous clinical phenotypes and reduced plasma factor VII activity.
Wei Luo +3 more
doaj +2 more sources
The complex formed between the procoagulant serine protease activated factor VII (FVII) and the membrane protein tissue factor, exposed on the vascular lumen upon injury, triggers the initiation of blood clotting. This review describes the clinical picture of FVII deficiency and provides information on diagnosis and management of the disease.
G. Mariani, BERNARDI, Francesco
openaire +3 more sources
Hereditary Factor VII Deficiency
rare autosomal recessive inherited blood ...
semanticscholar +1 more source
The EAHAD blood coagulation factor VII variant database
Hereditary blood coagulation factor VII (FVII) deficiency is a rare autosomal recessive bleeding disorder resulting from variants in the gene encoding FVII (F7).
M. Giansily-Blaizot +7 more
semanticscholar +1 more source
Polymorphisms in F2, F7, and PAI1 genes in men with coronary atherosclerosis
Aim. To study the associations of polymorphisms in F2, F7, and PAI1 genes with the presence of vulnerable plaque in coronary arteries (CA) and the blood concentration of proteins encoded by these genes.Material and methods.
E. V. Stryukova +7 more
doaj +1 more source
Background Factor VII deficiency is a rare bleeding disorder caused by a deficiency of clotting factor VII. However, there have been some case reports of venous thrombosis in patients with factor VII deficiency, especially underlying the prothrombotic ...
Lei Li +4 more
doaj +1 more source
Congenital Factor VII Deficiency Presenting with Isolated Recurrent Hematuria: A Case Report
Introduction: Factor VII deficiency is a rare congenital coagulopathy disorder. In most cases this disorder is diagnosed in childhood. Common symptoms of congenital factor VII deficiency are different and consist of mucosal cutaneous hemorrhage ...
Shahla Ansary Damavandi +3 more
doaj +1 more source

