Results 21 to 30 of about 13,117,018 (331)

Factor VII deficiency – an enigma; clinicohematological profile in 12 cases

Hematology, 2018
Objective: Factor VII deficiency is the commonest of the rare bleeding disorders with limited knowledge on clinical profile. The objective of this study was to study the prevalence and clinico-hematological profile of factor VII-deficient patients ...
P. Tripathi, P. Mishra, R. Ranjan, S. Tyagi, T. Seth, R. Saxena   +5 more
semanticscholar   +1 more source

Evaluation of Clinical Features, Laboratory Findings and Treatment of Patients with Rare Factor Deficiency: A Retrospective Single Center Experience

Çocuk Dergisi, 2023
Objective: Patients with a rare factor deficiency (RFD) may be asymptomatic or present with life-threatening bleeding. Studies have shown no direct relationship between factor activity level and bleeding severity, with difficulties being experienced in ...
Işık Odaman Al, Tuba Hilkay Karapınar, Salih Gözmen, Yeşim Oymak   +3 more
doaj   +1 more source

The international, prospective Glanzmann Thrombasthenia Registry: treatment modalities and outcomes of non-surgical bleeding episodes in patients with Glanzmann thrombasthenia

Haematologica, 2015
Standard treatment for Glanzmann thrombasthenia is platelet transfusion. Recombinant activated factor VII has been shown to be successful in patients with Glanzmann thrombasthenia with platelet antibodies or who are refractory to platelet transfusions ...
Giovanni Di Minno, Rainer B Zotz, Roseline d’Oiron, Niels Bindslev, Matteo Nicola Dario Di Minno, Man-Chiu Poon   +5 more
doaj   +1 more source

Identification of two different coagulation phenotypes in people living with HIV with undetectable viral replication

Scientific Reports, 2021
Altered coagulation has been reported in people living with HIV (PLWH) with ongoing viral replication and may predispose to cardiovascular diseases. However, less is known about coagulation in PLWH with undetectable viral replication.
Asbjørn Fink, Andreas Dehlbæk Knudsen, Rebekka Faber Thudium, Jakob Hjorth Von Stemann, Shoaib Afzal, Jens Lundgren, Ditte Marie Kirkegaard-Klitbo, Sisse Rye Ostrowski, Børge G. Nordestgaard, Susanne Dam Nielsen   +9 more
doaj   +1 more source

Factor VII verona coagulation disorder: double heterozygosis with an abnormal factor VII and heterozygous factor VII deficiency [PDF]

Blood, 1977
A family with a peculiar defect of factor VII is described. The propositi, a brother and sister, were born of a nonconsanguineous marriage and presented a mild to moderate bleeding tendency since childhood (epistaxis, excessive bleeding after tooth extraction).
A, Girolami, G, Falezza, G, Patrassi, M, Stenico, L, Vettore   +4 more
openaire   +3 more sources

Acute Myelogenous Leukemia With Trisomy 8 and Concomitant Acquired Factor VII Deficiency

Journal of Investigative Medicine High Impact Case Reports, 2019
Acquired isolated factor VII deficiency is a rare bleeding disorder and has been reported in 31 cases. This is in contrast to congenital factor VII deficiency, which while also infrequent is the most common rare congenital bleeding disorder.
Leila Moosavi MD, Jonathan Bowen BSc, Jeffrey Coleman MD, Arash Heidari MD, Everardo Cobos MD   +4 more
doaj   +1 more source

Case of concurrent factor VII and factor XI deficiencies manifesting as spontaneous lower extremity compartment syndrome

Clinical Case Reports, 2022
Factor VII and XI deficiencies are rare bleeding disorders typically associated with mild or provoked bleeding. This case report describes a patient with factor VII and XI deficiencies with an unprovoked episode of lower extremity hematoma causing ...
Joseph P. Marshalek, David Yashar, Karen Huynh, Sarah Tomassetti   +3 more
doaj   +1 more source

Congenital factor VII deficiency presenting first time as isolated recurrent hematuria at late age

Saudi Journal of Kidney Diseases and Transplantation, 2019
Hematological conditions rarely present as isolated hematuria. Factor VII deficiency is a rare congenital coagulopathy inherited as autosomal recessive pattern. It usually presents a severe life-threatening bleeding at an early age.
Suman Sethi, Sudhir Mehta, Nitin Sethi, Vikas Makkar, Simran Kaur, Manpreet Kaur Jhingar   +5 more
doaj   +1 more source

Hereditary combined deficiency of vitamin K–dependent clotting factors presenting as postoperative haemorrhage in a Syrian adolescent: a likely VKCFD type 2 phenotype

European Journal of Case Reports in Internal Medicine
Hereditary combined deficiency of vitamin K–dependent clotting factors (VKCFD) is a rare autosomal recessive disorder characterized by reduced activity of factors II, VII, IX, and X despite normal vitamin K levels.
Mahmoud Alhamadeh Alswij, Mais Musleh, Abdulhalim Mohamed Alyousef, Nizar Alsheekh Ahmad, Abdullatif AlStem, Hadi Ataya   +5 more
doaj   +1 more source

A thrombophilic allele of clotting Factor VII/VIIa promoting recurrent pulmonary emboli, clinical details, and a structural model of the altered protein: a case report

Journal of Medical Case Reports, 2023
Background The clotting or hemostasis system is a meticulously regulated set of enzymatic reactions that occur in the blood and culminate in formation of a fibrin clot.
Kenneth Newman, Fevzi Daldal, Andrew Dancis   +2 more
doaj   +1 more source