Results 11 to 20 of about 448,079 (362)
The complex formed between the procoagulant serine protease activated factor VII (FVII) and the membrane protein tissue factor, exposed on the vascular lumen upon injury, triggers the initiation of blood clotting. This review describes the clinical picture of FVII deficiency and provides information on diagnosis and management of the disease.
G. Mariani, BERNARDI, Francesco
semanticscholar +6 more sources
Factor VII Deficiency: Clinical Phenotype, Genotype and Therapy [PDF]
Factor VII deficiency is the most common among rare inherited autosomal recessive bleeding disorders, and is a chameleon disease due to the lack of a direct correlation between plasma levels of coagulation Factor VII and bleeding manifestations. Clinical
Mariasanta Napolitano+2 more
openalex +2 more sources
A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency [PDF]
Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps.
Won Seok Lee, Young Sil Park
doaj +4 more sources
Acquired deficiency of coagulation factor VII
Factor VII (FVII) is found in small amounts in plasma and has a very short half-life in circulation. FVII is vitamin K-dependently synthesized in the liver. As such, hepatopathies, vitamin K deficiency, or use of vitamin K antagonists is the cause of acquired deficiency.
Vanessa Afonso da Silva+2 more
doaj +5 more sources
Replacement therapy for bleeding episodes in factor VII deficiency: A prospective evaluation [PDF]
Patients with inherited factor VII (FVII) deficiency display different clinical phenotypes requiring ad hoc management. This study evaluated treatments for spontaneous and traumatic bleeding using data from the Seven Treatment Evaluation Registry (STER).
Auerswald,G+14 more
core +3 more sources
Combined Factor VII and X Deficiency [PDF]
Factor VII deficiency and factor X deficiency and very rare disorders individually. Combined Factor VII and X is a rare congenital blood disorder with very few cases reported in the literature.
Gursharan Singh Narang,+2 more
doaj +1 more source
A 52 year-old male presented with neck pain after undergoing thyroidectomy for a goiter three weeks prior which was complicated by a neck hematoma requiring evacuation.
Anthony L. Nguyen+3 more
doaj +2 more sources
Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis [PDF]
Factor VII (FVII) is an important, vitamin K-dependent clotting factor. Acquired FVII deficiency is a rare entity that is associated with serious bleeding complications.
Emily B. Wolf MD+9 more
doaj +2 more sources
Despite the exhaustive screening of F7 gene exons and exon-intron boundaries and promoter region, a significant proportion of mutated alleles remains unidentified in patients with coagulation factor VII deficiency.
Paolo Ferraresi+8 more
doaj +2 more sources
Factor VII deficiency: a rare genetic bleeding disorder in a 7-year-old child: a case report [PDF]
Background Factor VII deficiency is a rare inherited bleeding disorder that has similar clinical presentation to hemophilia. Case report A 7-year-old male child of African origin experienced recurrent nasal bleeding since 3 years of age and recurrent ...
Hajaj Mohamed Salum+8 more
doaj +2 more sources