Results 11 to 20 of about 448,079 (362)

Factor VII Deficiency [PDF]

open access: yesSeminars in Thrombosis and Hemostasis, 2009
The complex formed between the procoagulant serine protease activated factor VII (FVII) and the membrane protein tissue factor, exposed on the vascular lumen upon injury, triggers the initiation of blood clotting. This review describes the clinical picture of FVII deficiency and provides information on diagnosis and management of the disease.
G. Mariani, BERNARDI, Francesco
semanticscholar   +6 more sources

Factor VII Deficiency: Clinical Phenotype, Genotype and Therapy [PDF]

open access: goldJournal of Clinical Medicine, 2017
Factor VII deficiency is the most common among rare inherited autosomal recessive bleeding disorders, and is a chameleon disease due to the lack of a direct correlation between plasma levels of coagulation Factor VII and bleeding manifestations. Clinical
Mariasanta Napolitano   +2 more
openalex   +2 more sources

A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency [PDF]

open access: yesKorean Journal of Pediatrics, 2010
Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps.
Won Seok Lee, Young Sil Park
doaj   +4 more sources

Acquired deficiency of coagulation factor VII

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2015
Factor VII (FVII) is found in small amounts in plasma and has a very short half-life in circulation. FVII is vitamin K-dependently synthesized in the liver. As such, hepatopathies, vitamin K deficiency, or use of vitamin K antagonists is the cause of acquired deficiency.
Vanessa Afonso da Silva   +2 more
doaj   +5 more sources

Replacement therapy for bleeding episodes in factor VII deficiency: A prospective evaluation [PDF]

open access: green, 2013
Patients with inherited factor VII (FVII) deficiency display different clinical phenotypes requiring ad hoc management. This study evaluated treatments for spontaneous and traumatic bleeding using data from the Seven Treatment Evaluation Registry (STER).
Auerswald,G   +14 more
core   +3 more sources

Combined Factor VII and X Deficiency [PDF]

open access: yesOnline Journal of Health & Allied Sciences, 2011
Factor VII deficiency and factor X deficiency and very rare disorders individually. Combined Factor VII and X is a rare congenital blood disorder with very few cases reported in the literature.
Gursharan Singh Narang,   +2 more
doaj   +1 more source

Acquired factor VII deficiency causing severe bleeding disorder secondary to AL amyloidosis of the liver

open access: yesHematology Reports, 2018
A 52 year-old male presented with neck pain after undergoing thyroidectomy for a goiter three weeks prior which was complicated by a neck hematoma requiring evacuation.
Anthony L. Nguyen   +3 more
doaj   +2 more sources

Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis [PDF]

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2023
Factor VII (FVII) is an important, vitamin K-dependent clotting factor. Acquired FVII deficiency is a rare entity that is associated with serious bleeding complications.
Emily B. Wolf MD   +9 more
doaj   +2 more sources

Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency

open access: yesHaematologica, 2020
Despite the exhaustive screening of F7 gene exons and exon-intron boundaries and promoter region, a significant proportion of mutated alleles remains unidentified in patients with coagulation factor VII deficiency.
Paolo Ferraresi   +8 more
doaj   +2 more sources

Factor VII deficiency: a rare genetic bleeding disorder in a 7-year-old child: a case report [PDF]

open access: yesJournal of Medical Case Reports, 2023
Background Factor VII deficiency is a rare inherited bleeding disorder that has similar clinical presentation to hemophilia. Case report A 7-year-old male child of African origin experienced recurrent nasal bleeding since 3 years of age and recurrent ...
Hajaj Mohamed Salum   +8 more
doaj   +2 more sources

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