Results 91 to 100 of about 12,736,036 (293)

Novel Bioresorbable Bone Wax for Potentiated Hemostasis and Osteogenesis

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The synthesized bioresorbable bone wax material for hemostasis and osteogenesis. The preparation process of the novel resorbable bone wax and its mechanism of accelerating coagulation and promoting osteoregeneration through blood cell aggregation. Abstract Orthopedic surgery faces dual challenges of uncontrolled bleeding and poor bone regeneration at ...
Longbao Feng, Yanbin Lu, Pengyu Fu, Shaojun Li, Pengning She, Yang xiao, Jiaming Ye, Wanqi Li, Shaochuan Li, Wei Xue, Rui Guo   +10 more
wiley   +1 more source

Pediatric cardiac surgery under cardiopulmonary bypass in factor VII deficiency

The Turkish Journal of Pediatrics, 2010
We present a case of an atrial septal defect repair under cardiopulmonary bypass in a child with factor VII deficiency. A four-year-old girl, with the diagnosis of secundum atrial septal defect, was referred to surgery. Coagulation tests showed an
Ozan Emiroğlu, Zeynep Eyileten, Tayfun Uçar, Talya Ileri   +3 more
doaj  

Cost effectiveness of recombinant factor VIIa for treatment of intracerebral hemorrhage

BMC Neurology, 2008
Background Phase I/II placebo-controlled clinical trials of recombinant Factor VIIa (rFVIIa) suggested that administration of rFVIIa within 4 hours after onset of intracerebral hemorrhage (ICH) is safe, limits ICH growth, and improves outcomes. We sought
Eckman Mark H, Kissela Brett M
doaj   +1 more source

A Comparison between Recombinant Activated Factor VII (Aryoseven) and Novoseven in Patients with Congenital Factor VII Deficiency [PDF]

, 2015
In order to establish the efficacy and biosimilar nature of AryoSeven to NovoSeven in the treatment of congenital factor VII (FVII) deficiency, patients received either agent at 30 1/4g/kg, intravenously per week for 4 weeks, in a randomized fashion. The
Abolghasemi, H., Ahmadinejad, M., Baghaeipour, M.R., Dehdezi, B.K., Eshghi, P., Faranoush, M., Fayazfar, R., Heshmat, R., Hoorfar, H., Kamyar, K., Karimi, M., Khoeiny, B., Managhchi, M., Mehrvar, A., Mirbehbahani, N.B., Naderi, M., Toogeh, G.   +16 more
core  

Induction of endothelial cell proliferation by recombinant and microparticle-tissue factor involves β1-integrin and extracellular signal regulated kinase activation [PDF]

, 2010
Objective: Increased levels of circulating tissue factor (TF) in the form of microparticles increase the risk of thrombosis. However, any direct influence of microparticle-associated TF on vascular endothelial cell proliferation is not known.
Collier, Mary E. W., Ettelaie, Camille
core   +1 more source

Nanoplastics trigger glial–neuronal collagen signaling miscommunication to exacerbate cognitive impairment in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) is a progressive neurodegenerative disorder with limited treatments and poorly defined environmental risks. Micro‐ and nanoplastics (MNPs) are widespread pollutants linked to neurotoxicity, but their role in AD remains unclear.
Yizhou Zhong, Bingchi Fan, Xiaohong Yang, Yuji Huang, Boxuan Liang, Zhiming Li, Xiaohu Ren, Hongyi Xian, Yanhong Deng, Yu Feng, Ruobing Bai, Xiyun Huang, Xiaoqing Chen, Hao Li, Shiyue Tang, Lichun Ma, Chen Yang, Jianjun Liu, Xifei Yang, Xingfen Yang, Zhenlie Huang   +20 more
wiley   +1 more source

Human Protein Z as the Second Known Heme‐Binding Protein from the Endogenous Blood Coagulation Inhibitor System

ChemBioChem, Volume 27, Issue 1, January 2026.
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley   +1 more source

Accuracy and Limitations of the Pair‐Selected Multilevel Approach for DLPNO Coupled Cluster: Extensive Benchmark for Closed‐Shell Organic Reactions

ChemPhysChem, Volume 27, Issue 1, January 2026.
This graphic shows the error distribution for pericyclic reactions calculated with the multilevel approach under investigation and illustrates that outliers are critically analyzed using different approximations for the triples correction. Reliable approximations to coupled‐cluster (CC) methods are highly desirable for accurate yet efficient ...
Nalini Gurav, Nadim Ramez, Lukas Lampe, Johannes Neugebauer   +3 more
wiley   +1 more source

Evidence and desperation in off-label prescribing: recombinant factor VIIa

British medical journal, 2012
Wendy Lipworth and colleagues explore why clinicians prescribe recombinant factor VIIa off-label for major haemorrhage, despite a lack of supporting evidence—and why this ...
W. Lipworth, I. Kerridge, M. Little, R. Day   +3 more
semanticscholar   +1 more source

Tissue Factor Structure and Function

Scientifica, 2012
Tissue factor (TF) is an integral membrane protein that is essential to life. It is a component of the factor VIIa-TF complex enzyme and plays a primary role in both normal hemostasis and thrombosis.
Saulius Butenas
doaj   +1 more source