Results 61 to 70 of about 15,991 (171)

The effect of perioperative erythropoietin‐stimulating agents and intravenous iron on patient outcomes following solid organ transplantation: A systematic review

Transfusion Medicine, EarlyView.
Abstract Solid organ transplant is associated with high rates of anaemia and transfusion, but there is little comparative data on interventions such as erythropoietin‐stimulating agents (ESAs) and intravenous (IV) iron. We conducted a systematic review examining the association of ESAs and IV iron with outcomes in adults undergoing solid organ ...
Frank Lee, Quentin Eichbaum, Christine Cserti‐Gazdewich, Darren Mullane, Frederick W. Lombard, Jeremy W. Jacobs, Katerina Pavenski, Marina Englesakis, Alexander Dotto, Terry Cho, Andrés Leonard‐Reixa, Jacqueline Trudeau, Andrew W. Shih, Justyna Bartoszko   +13 more
wiley   +1 more source

Phenotyping of Fontan‐Associated Renal Physiology and Disease

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
In patients with a Fontan circulation, both kidney function and glomerular injury progressively decline with age, with a stronger decline than in healthy individuals. Additionally, intrarenal haemodynamics in patients with a Fontan circulation demonstrate decreased venous and arterial compliance, evident through elevated venous impedance and renal ...
Gaston van Hassel, Jozine M. ter Maaten, Iris E. Beldhuis, Eryn T. Liem, Bastiaan Zwart, Stephan J. L. Bakker, Rolf M. F. Berger, Joost P. van Melle   +7 more
wiley   +1 more source

Tissue Factor Structure and Function

Scientifica, 2012
Tissue factor (TF) is an integral membrane protein that is essential to life. It is a component of the factor VIIa-TF complex enzyme and plays a primary role in both normal hemostasis and thrombosis.
Saulius Butenas
doaj   +1 more source

THE EFFICACY OF RECOMBINANT ACTIVATED FACTOR VII (COAGIL VII) FOR TREATMENT HAEMORRHAGE AND HAEMOSTASIS DISORDES DURING THORACIC AORTA OPERATIONS

Вестник анестезиологии и реаниматологии, 2019
Goal: to evaluate the efficacy and safety of domestic (home-produced) recombinant factor VIIa (Coagil VII) for massive bleeding and haemostasis disordes treatment in thoracic aorta surgery. Methods.
N. A. TREKOVA, D. A. GUSKOV, A. V. GONCHAROVA, B. A. AKSELROD   +3 more
doaj   +1 more source

Symbiosis‐associated UMAMIT transporters required for establishing efficient nitrogen fixation in Medicago truncatula

New Phytologist, Volume 250, Issue 1, Page 530-546, April 2026.
Summary To address a critical gap in understanding amino acid transport in legume–Rhizobium symbiosis, we investigated the role of symbiosis‐associated USUALLY MULTIPLE ACIDS MOVE IN AND OUT TRANSPORTERS (UMAMITs) in Medicago truncatula nodulation.
Courtney S. Winning, María Isabel Rubia, Wei Liu, Daniel Bronitt, Ángel María Zamarreño, José María García‐Mina, Penelope Smith, Estíbaliz Larrainzar, Michael A. Djordjevic   +8 more
wiley   +1 more source

Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang, Shucheng Jin, Penghui Guo, Yuying Yin, Yichun Hua, Xiaosheng Ding, Zhe Zhang, Shuo Chen, Xu Han, Baowang Li, Yan Liu, Xiaoyan Li, Deling Li, Jing Jing, Wei Shi, Wang Jia   +15 more
wiley   +1 more source

Acquired Hemophilia A Presenting as Intramuscular Hematoma

Journal of Investigative Medicine High Impact Case Reports, 2018
Acquired hemophilia A poses a clinical and diagnostic challenge. Although rare, it is still the most common acquired factor deficiency. We present a case of acquired hemophilia A diagnosed in a 71-year-old female who presented with a right thigh hematoma
Ghassan Al-Shbool MD, Anusha Vakiti MD
doaj   +1 more source

Ciliary Defects in Inherited Retinal Diseases

Advanced Genetics, Volume 7, Issue 1, March 2026.
The photoreceptor cilium is a specialized sensory organelle essential for vision. This review systematically summarizes the structural and functional defects of the cilium that lead to inherited retinal diseases (IRDs). It highlights key pathogenic genes, elucidates molecular mechanisms of degeneration, and evaluates emerging therapeutic strategies ...
Guizhi Guo, Lin Li, Jun Zhou, Jie Ran
wiley   +1 more source

Optimal use of recombinant factor VIIa in the control of bleeding episodes in hemophilic patients

Drug Design, Development and Therapy, 2010
John PuetzSaint Louis University, Department of Pediatrics, St Louis, Missouri, USAAbstract: One of the last remaining clinical hurdles in the treatment of people with hemophilia is the development of inhibitors. Alloantibodies or autoantibodies directed
John Puetz
doaj  

Thrombin Generation Induced by Complement Component C1q Interaction With the Receptor for the Globular Head of C1q on Adventitial Fibroblasts and Vascular Smooth Muscle Cells

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Introduction Heightened inflammatory and thrombotic processes are common hallmarks of vascular diseases. The interaction between these two processes remains unclear and a better understanding of these links can allow for the design of more effective treatment options.
Christopher Thor Freda, Wei Yin, Berhane Ghebrehiwet, David A. Rubenstein   +3 more
wiley   +1 more source