Results 81 to 90 of about 19,325,472 (304)

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Combined Factor VII and X Deficiency

Online Journal of Health & Allied Sciences, 2011
Factor VII deficiency and factor X deficiency and very rare disorders individually. Combined Factor VII and X is a rare congenital blood disorder with very few cases reported in the literature.
Gursharan Singh Narang,, Sunita Arora,, Jivtesh Singh Pahwa,   +2 more
doaj  

Irreducibility criterion, irreducible factors, Newton polygon techniques [PDF]

arXiv, 2020
Jakhar shown that for $f(x)=a_nx^n + a_{n-1}x^{n-1}+\cdot+ a_0$ ($a_0\neq 0$) is a polynomial with rational coefficients, if there exists a prime integer $p$ satisfying $\nu_p(a_n)=0$ and $n\nu_p(a_i)\ge (n-i)\nu_p(a_0)> 0$ for every $0\le i\le n-1$, then $f(x)$ has at most $gcd(\nu_p(a_0),n)$ irreducible factors over the field $\mathbb{Q}$ of rational
arxiv  

Effect of Neutralizing Sera on Factor X-Mediated Adenovirus Serotype 5 Gene Transfer

Journal of Virology, 2008
The deployment of adenovirus serotype 5 (Ad5)-based vectors is hampered by preexisting immunity. When such vectors are delivered intravenously, hepatocyte transduction is mediated by the hexon-coagulation factor X (FX) interaction.
A. Parker, S. Waddington, S. Buckley, J. Custers, M. Havenga, N. Van Rooijen, J. Goudsmit, J. McVey, S. Nicklin, A. Baker   +9 more
semanticscholar   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

On a conjecture on shifted primes with large prime factors, II [PDF]

Bull. Aust. Math. Soc. 111 (2025) 48-55
Let $\mathcal{P}$ be the set of primes and $\pi(x)$ the number of primes not exceeding $x$. Let also $P^+(n)$ be the largest prime factor of $n$ with convention $P^+(1)=1$ and $$ T_c(x)=\#\left\{p\le x:p\in \mathcal{P},P^+(p-1)\ge p^c\right\}. $$ Motivated by a 2017 conjecture of Chen and Chen, we show that for any $8/9\le c<1$ $$ \limsup_{x\rightarrow\
arxiv   +1 more source

Factorization of Holomorphic Matrices and Kazhdan's property (T) [PDF]

arXiv, 2022
In this article we deduce some algebraic properties for the group $\mathrm{Sp}_{2n} (\mathcal{O}(X))$ of holomorphic symplectic matrices on a Stein space $X$: holomorphic factorization, exponential factorization, and Kazhdan's property (T). In holomorphic factorization we combine a recent result of the third author and K-theory tools to give explicit ...
arxiv  

Diagnosis and treatment of inherited factor X deficiency

Haemophilia, 2008
Summary.  Factor X is a vitamin K‐dependent, liver‐produced serine protease that serves a pivotal role in coagulation as the first enzyme in the common pathway to fibrin formation.
Deborah L Brown, P. Kouides
semanticscholar   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Factorization of a class of composed polynomials [PDF]

arXiv, 2018
In this paper, we provide the degree distribution of irreducible factors of the composed polynomial $f(L(x))$ over $\mathbb F_q$, where $f(x)\in \mathbb F_q[x]$ is irreducible and $L(x)\in \mathbb F_q[x]$ is a linearized polynomial. We further provide some applications of our main result, including lower bounds for the number of irreducible factors of $
arxiv