Results 121 to 130 of about 4,918,610 (234)
A young dog presented with progressive unilateral hindlimb lameness and marked erythrocytosis. Diagnostic investigations excluded secondary causes and confirmed primary erythrocytosis. Targeted vascular ultrasonography identified a right external iliac venous thrombus as the suspected cause of lameness.
Robyn Belch +8 more
wiley +1 more source
The cooperative reactivity characteristic of molecular dinuclear nickel complexes is transferred to mesoporous silica through a systematic immobilization strategy. The resulting material preserves the key features of the bimetallic motif within a robust heterogeneous framework, demonstrating how molecular design principles can be translated into well ...
Jitpisut Poolwong +4 more
wiley +2 more sources
Genome Aging in Women: Hematopoietic Loss of X Chromosome as An Exemplar
As studies at the intersection of genetics and aging are rapidly advancing, genome aging provides a novel mechanism by which aging phenotypes occur. In this Review, the authors examine the rise, expansion, and the consequences of X chromosome loss in female blood cells.
Xihan Guo, Xueqin Dai
wiley +1 more source
Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley +1 more source
Linda Tahaineh,1 Sahar M Edaily,1 Shadi F Gharaibeh2 1Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology (JUST), Irbid, Jordan; 2Department of Pharmaceutical Sciences, Faculty of Pharmacy, Jerash University,
Tahaineh L, Edaily SM, Gharaibeh SF
core
The redox‐sensitive transcriptional repressor ZmMS1 coordinates reactive oxygen species homeostasis and lipid allocation for pollen exine and anther cuticle formation. Loss or precocious expression of ZmMS1 causes male sterility. Constitutive overexpression induces dwarfism and semi‐sterility. These findings enable flexible maize male‐sterility systems
Quancan Hou +13 more
wiley +1 more source
Oral factor Xa inhibitor underutilization following lower extremity peripheral vascular intervention. [PDF]
Bhuta S +6 more
europepmc +1 more source
Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage. [PDF]
BACKGROUND Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion ...
Kallmuenzer, B +175 more
core +2 more sources
We extend a widely used C3‐photosynthesis model to account for various photorespiratory bypasses, thereby, providing a useful resource and framework that enforces future novel bypass work and scrutinize if the results go counter to theory. Our model analyses show that of the 17 published bypass pathways, full‐decarboxylating bypasses (that have been ...
Xinyou Yin +3 more
wiley +1 more source
Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan +8 more
wiley +1 more source

