Results 101 to 110 of about 4,918,610 (234)

Oral Soft Tissue Biopsy in Patients Receiving Direct Oral Anticoagulants: A Prospective Cohort Study on Bleeding Outcomes

Oral Diseases, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are the first‐line therapy for stroke prevention in non‐valvular atrial fibrillation and venous thromboembolism. While evidence supports their continuation during routine dental procedures such as tooth extractions, data on oral soft tissue biopsies remain limited.
Rossana Izzetti, Chiara Cinquini, Antonio Barone, Marco Nisi   +3 more
wiley   +1 more source

Mechanism and kinetics study of MG1113, an anti–tissue factor pathway inhibitor antibody promoting hemostasis in hemophilia

Research and Practice in Thrombosis and Haemostasis
Background: Targeting tissue factor pathway inhibitor (TFPI) is an emerging hemostatic rebalancing strategy for hemophilia. MG1113 is a humanized monoclonal antibody designed to specifically bind the Kunitz domain (KD)2 of TFPI.
Heechun Kwak, Hyun-Ja Nam, Sung Ho Hwang
doaj   +1 more source

Heparin enhances the inhibition of factor Xa by protein C inhibitor in the presence but not in the absence of Ca2+

, 2009
Protein C inhibitor (PCI) is a versatile serine protease inhibitor with both pro- and anticoagulant and other properties. Interactions of certain ligands with PCI, including heparin, affect its specificity for proteases.
Sun, Wei,, Eriksson, Anna S,, Schedin-Weiss, Sophia,   +2 more
core   +1 more source

Management of Left Atrial Appendage Thrombi and Spontaneous Echo Contrast

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background To analyze the efficacy and safety of various anticoagulation strategies/regimen used for managing thrombus or spontaneous echo contrast in the left atrial appendage. Methods Thrombus or spontaneous echo contrast in the left atrial appendage was detected via transesophageal echocardiography in 83 patients, most often during a stroke
Timnou Bekouti Jean, Ravakiniaina Ranaivosoa Mialy, Ateba Ateba Nelly Stella, Tsague Kegni Hermann, Rambolarimanana Mansh, Ndobo Julia Valérie, Imbey Eheth Levy, Maury Philippe, Diawara Alpha, Roynard Jean Louis, Boombhi Jerome Hilaire   +10 more
wiley   +1 more source

Linguistic Citizenship Inside and Beyond the Coloniality of English

World Englishes, EarlyView.
ABSTRACT This article describes how Black students within educational settings are positioned in relation to English, while also foregrounding fleeting moments of liberation and transformation. We focus specifically on the role of English within the linguistic repertoires of Black students in the Technical and Vocational Education and Training sector ...
Alexa Anthonie, Marcelyn Oostendorp
wiley   +1 more source

Effects of rivaroxaban and apixaban on intimal hyperplasia in rabbits

Turkish Journal of Vascular Surgery, 2022
Aim: Intimal hyperplasia causes vascular occlusion and its optimal treatment is unknown. In this study, we evaluated the effectiveness of Apixaban and Rivaroxaban treatment for preventing intimal hyperplasia in rabbits. Material and Methods: The rabbits
Mustafa Baris Kemahli, Tugra Gencpinar, Huseyin Dursun, Cagatay Bilen, Pinar Akokay, Serdar Bayrak, Abidin Cenk Erdal   +6 more
doaj  

Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N- [3-fluoro-2‘-(aminosulfonyl)[1,1‘-biphenyl)]-4-yl]-1H-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor

, 2016
Factor Xa, a serine protease, is at the critical juncture between the intrinsic and extrinsic pathways of the coagulation cascade. Inhibition of factor Xa has the potential to provide effective treatment for both venous and arterial thrombosis.
Donald J. P. Pinto (2470099), Robert Bruckner (3016782), Ruth R. Wexler (1550446), Karen A. Rossi (1601821), Joseph M. Luettgen (1550428), Patrick Y. S. Lam (1565911), Lori L. Bostrom (3016791), Matthew R. Wright (3011232), Richard S. Alexander (2470093), Haiying Chen (9771), Pancras C. Wong (1601836), Steven Bai (2375269), Robert M. Knabb (1846204), Brian L. Wells (3016794), Angela Smallwood (1450567), Robert A. Galemmo, (3016779), James R. Pruitt (3016785), Debra Burdick (3016788), Spencer Drummond (3016776)   +18 more
core   +1 more source

Surface Ligand Engineering in Quantum Dot Photocatalysis: Mechanisms, Design Principles, and Applications

Advanced Chemical Engineering, Volume 1, Issue 2, December 2026.
Surface ligands govern quantum dot photocatalysis through thermodynamic band‐edge tuning, kinetic charge‐transfer regulation, and microenvironmental control. Rational ligand engineering, using short‐chain, inorganic, conjugated, or dual‐ligand systems, enables efficient solar fuel production, selective organic transformations, environmental remediation,
Yali Weng, Huakang Yang, Zining Zhang, Yue Zhou, Dongxiang Luo, Xiao Liu   +5 more
wiley   +1 more source

An In Vitro Study Simulating Prophylactic Anticoagulation in Haemophilia A and B

eJHaem, Volume 7, Issue 6, December 2026.
ABSTRACT Introduction Patients with haemophilia A (HA) and haemophilia B (HB) are at increased bleeding risk. A recent guidance document suggests considering pharmacological thromboprophylaxis on a case‐by‐case basis in these patients undergoing surgery at high‐risk of venous thromboembolism.
Nicoletta Riva, Kevin Vella, Kieron Hickey, Nigel Debattista, Carmel Grima, Denise Borg‐Aquilina, Liberato Camilleri, Jiong Jiong Guo, Alexander Gatt   +8 more
wiley   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

European Journal of Haematology, Volume 117, Issue 6, Page 1421-1441, December 2026.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto, Silvia Sorella, Erminia Baldacci, Massimo Breccia, Sabina Chiaretti, Marcello Capriata, Livia Donzelli, Gianna Maria D'Elia, Salvatore Giacomo Morano, Ilaria Del Giudice, Maurizio Martelli, Cristina Santoro, Antonio Chistolini   +12 more
wiley   +1 more source