Results 101 to 110 of about 18,017 (247)

Direct Factor Xa Inhibitors Versus Warfarin in Non-Valvular Atrial Fibrillation: Efficacy, Safety, Cost, and Reversibility

open access: yes, 2016
Atrial fibrillation is a common cause for stroke. Vitamin K antagonists such as warfarin are an effective prophylactic medication to prevent stroke in patients with atrial fibrillation.
Jacobs, Cory D.
core  

Acute prefrontal hemodynamic responses to intermittent theta burst stimulation correlate with current depression and episode recurrence: A cross‐sectional study

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Background Mounting evidence has indicated that multiple major depressive disorder (MDD) episodes are correlated with brain morphometric changes that confer an increased recurrence risk. Functional abnormalities underlying this recurrent vulnerability remain underexplored.
Minxia Jin   +12 more
wiley   +1 more source

Role of Prothrombin Complex Concentrates in Reversal of Direct Oral Anticoagulant Effects

open access: yesBezmiâlem Science
Objective: The aim of this study is to evaluate the efficacy and safety of four-factor prothrombin complex concentrate in reversing the anticoagulant effect in patients presenting to the emergency department with bleeding associated with direct oral ...
Gökhan ERSUNAN   +4 more
doaj   +1 more source

New factor Xa inhibitors based on 1,2,3,4-tetrahydroquinoline developed by molecular modelling

open access: yes
Factor Xa is a serine protease representing a crucial element in the coagulation process and an attractive target for anticoagulant therapy. At the present time there are several chemical classes of factor Xa inhibitors with proven activity. Furthermore,
Krysin M.   +10 more
core   +1 more source

Invalid Nucleic Acid Test Results May Limit Deceased Donor Organ Utilization

open access: yesTransplant Infectious Disease, EarlyView.
Rare instances occur in which discriminatory NAT results cannot be resolved in deceased organ donor cases. When these events occur the impact on organ donation can be substantial. ABSTRACT Background Nucleic acid testing (NAT) is essential for detecting transmissible viral infections in deceased organ donors and guiding safe organ allocation.
Sara Dionne   +5 more
wiley   +1 more source

Factor Xa inhibitors in hemodialysis: OK-for now! [PDF]

open access: yesProc (Bayl Univ Med Cent), 2023
Banchs JE.
europepmc   +1 more source

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

open access: yesTransfusion, EarlyView.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa   +20 more
wiley   +1 more source

Clinical laboratory measurement of direct factor Xa inhibitors: Anti-Xa assay is preferable to prothrombin time assay

open access: yes, 2010
SummaryApixaban and other factor Xa (FXa) inhibitors are in late-stage clinical development for prevention and treatment of thromboembolic diseases. Although routine monitoring will not be required, in certain situations assessment of drug level may be ...
Charles Frost   +3 more
core   +1 more source

Bioresorbable Scaffolds for Coronary Arteries: Where Do We Stand Today?

open access: yesVIEW Medicine, Volume 1, Issue 1, August 2026.
Bioresorbable coronary scaffolds are moving from thick strut pitfalls to thinner, stronger, healing‐oriented designs. Integrating advances in materials, guided implantation with preparation, size, and postdilation steps, and resorption aligned to healing, we synthesize clinical evidence and chart a roadmap toward intelligent, transient platforms ...
Junya Matsuda   +5 more
wiley   +1 more source

Efficacy and Safety of Subcutaneous Efgartigimod PH20 in Adults With Primary Immune Thrombocytopenia (ADVANCE SC): A Multicenter, Randomized, Double‐Blinded, Placebo‐Controlled, Phase 3 Trial

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1494-1506, July 2026.
ABSTRACT Primary autoimmune thrombocytopenia (ITP) is characterized by thrombocytopenia, bleeding, and reduced health‐related quality of life. In the Phase 3 ADVANCE IV study, intravenous efgartigimod induced significant platelet count responses versus placebo in patients with chronic ITP. ADVANCE SC, a Phase 3, multicenter, randomized, double‐blinded,
Nichola Cooper   +546 more
wiley   +1 more source

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