Results 111 to 120 of about 18,017 (247)

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, Volume 45, Issue 4, Page 745-768, July/August 2026.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

Use of Andexanet Alfa for Factor Xa Inhibitor Reversal in US Verified Trauma Centers: A National Survey

Clinical and Applied Thrombosis/Hemostasis
Direct oral factor Xa inhibitors are replacing vitamin K-dependent antagonists as anticoagulation treatment in many clinical scenarios. Trauma centers are noting an increase in patients presenting on these medications.
Charles Fasanya MD, FRCS FACS, Abenámar Arrillaga MD FACS FCCP, Catherine Caronia MD, MBA, Lauren Rothburd BS, Tenzing Japhe BA, Younghee Hahn BS, Paul Joseph BS, Dajana Reci BA, Patricia Eckardt PhD, RN, FAAN   +8 more
doaj   +1 more source

Bright Ferritin for Non‐Invasive MRI Monitoring of the Fate of Transplanted hPSC‐Cardiomyocytes in the Infarcted Rat Heart

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 323-338, July 2026.
ABSTRACT Purpose To demonstrate that a recently reported bright ferritin magnetic resonance imaging (MRI) platform can track transplanted human pluripotent stem cell (hPSC)‐derived cardiomyocytes (hPSC‐CMs) longitudinally and on‐demand in the rat heart.
Keyu Zhuang, Faisal J. Alibhai, Beiping Qiang, Rocco Romagnuolo, Kyle D. W. Vollett, Bradley K. C. Freeman, M. Juliana Gomez‐Garcia, Tamilla Sadikov Valdman, Tameshwar Ganesh, Yu‐Qing Zhou, Hai‐Ying Mary Cheng, Michael A. Laflamme, Hai‐Ling Margaret Cheng   +12 more
wiley   +1 more source

Unraveling the Synergistic Activity‐Stability Enhancement of a High‐Entropy Perovskite Air Electrode for Dual Ceramic Electrochemical Cells

Advanced Science, Volume 13, Issue 34, 19 June 2026.
A high‐entropy air electrode material, Gd0.2Pr0.2Ba0.2Sr0.2Ca0.2FeO3−δ (GPBSCF), is developed for both solid oxide fuel cells and reversible protonic ceramic cells. Its enhanced activity stems from increased oxygen vacancies/holes. The stability improvement is attributed to lattice distortion, while thermal expansion reduction is synergistically due to
Ying Zhang, Yibei Wang, Zhilin Liu, Kuo Hu, Yaowen Wang, Zhen Wang, Xiyang Wang, Bingbing Niu, Wenquan Wang, Tianmin He   +9 more
wiley   +1 more source

Beyond CO2: Incorporating Bicarbonate, Dynamic Carbon Speciation, and Stoichiometric Plasticity Into Algal Growth Models

Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1491-1502, June 2026.
ABSTRACT The design of biological carbon capture systems to uptake carbon dioxide by photoautotrophic cultivation of algae has been proposed to mitigate atmospheric carbon emissions. Multiple models to predict algal growth as a function of nutrients have been proposed, but few have delved into the complex dynamic reactions of algal growth as influenced
Elizabeth Flanagan, Caye Drapcho, Mary Katherine Watson   +2 more
wiley   +1 more source

Comparing Direct Factor Xa Inhibitors and Warfarin in the Prevention of Stroke in Patients with Atrial Fibrillation

, 2016
Objective: To evaluate the overall efficacy, advantages, and disadvantages of treatment with direct factor Xa inhibitors as compared to warfarin in the prevention of stroke in patients with atrial fibrillation.
Lof, Alessandra, Pillai, Stephanie
core  

Novel factor Xa inhibitors for prevention and treatment of thromboembolic diseases.

, 2006
Novel anticoagulants to replace unfractionated heparins, low molecular weight heparins and vitamin K antagonists, are needed urgently. Coagulation factor Xa is an attractive target for drug development because of its position at the convergence of the ...
Kubitza, D;Haas, S
core   +1 more source

Variability in ACT Response to Standard UFH Bolus During PCI: A Prospective Study on Determinants of Subtherapeutic Anticoagulation

Catheterization and Cardiovascular Interventions, Volume 107, Issue 7, Page 2293-2303, June 1, 2026.
ABSTRACT Background Unfractionated heparin (UFH) remains the standard anticoagulant during percutaneous coronary intervention (PCI), with guidelines recommending a target activated clotting time (ACT) of ≥250 s. However, despite receiving a standardized bolus dose, many patients fail to achieve this target.
Manh Cuong Vu, Antonin Trimaille, Amandine Granier, Adrien Carmona, Anis Elidrissi, Marion Kibler, Laurence Jesel, Patrick Ohlmann, Laurent Sattler, Olivier Morel   +9 more
wiley   +1 more source

Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage.

BACKGROUND Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion ...
Kallmuenzer, B, Sharma, M, Toni, Danilo, Ekholm, Ella, Lang, W, Seiffge, David J., Bereczki, D, Robinson, Thompson G., Connolly, Stuart J., Lindgren, Arne G, Crowther, Mark, Lang, Wilfried, Gumbinger, C, Czlonkowska, A, Demchuk, Andrew M, Himmelmann, Anders, Veltkamp, Roland, Taylor, A, Verhamme, P, Tsivgoulis, G, Shoamanesh, A, Sandset, Else Charlotte, Cohen, AT, Ladenvall, P, Ekholm, E, Law, Andrew, Verhamme, Peter, Demchuk, Andrew M., Connolly, SJ, Knutsson, Mikael, Taylor, Amanda, Tanne, David, Robinson, Thompson G, Poli, Sven, Xu, LZ, Coutinho, Jonathan M, Xu, Lizhen, Molina, Carlos A, Law, A, Tsiplova, K, Himmelmann, A, Bereczki, Daniel, Roine, Risto O, Milling, TJ, Lemmens, R, Seiffge, David J, Roine, RO, Gumbinger, Christoph, Amarenco, Pierre, Seiffge, DJ, Sandset, EC, Tanne, D, Toni, D, Cohen, Alexander T, Christensen, H, Beyer-Westendorf, Jan, Kallmünzer, Bernd, Knutsson, M, Lindgren, Arne G., Roine, Risto O., Coutinho, Jonathan M., Sharma, Mukul, Molina, CA, Ladenvall, Per, Shoamanesh, Ashkan, Robinson, TG, Cohen, Alexander T., Connolly, Stuart J, Lemmens, Robin, Middeldorp, Saskia, Demchuk, AM, Karyakina, T, Tedim Cruz, V, Coutinho, JM, Veltkamp, R, ANNEXA-I Investigators, Mikulik, Robert, Christensen, Hanne, Lindgren, AG, Middeldorp, S, Amarenco, P, Becattini, Cecilia, Beyer Westendorf, J, Crowther, M, Mikulik, R, Tsiplova, Kate, Karyakina, Tetyana, Członkowska, Anna, Tedim-Cruz, Vitor, Tsivgoulis, Georgios, Milling, Truman John, Molina, Carlos A., Poli, S   +92 more
core   +1 more source

QSAR Study of Thiophene-Anthranilamides Based Factor Xa Direct Inhibitors

, 2020
QSAR studies were performed to understand the structure activity relationship (SAR) and to build the computational model to predict newer inhibitors with improved potency. In this study, a library of thiophene-anthranilamide based inhibitors of factor Xa
Preetpal S Sidhu
core