Results 111 to 120 of about 4,655,222 (236)

Management of Left Atrial Appendage Thrombi and Spontaneous Echo Contrast

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background To analyze the efficacy and safety of various anticoagulation strategies/regimen used for managing thrombus or spontaneous echo contrast in the left atrial appendage. Methods Thrombus or spontaneous echo contrast in the left atrial appendage was detected via transesophageal echocardiography in 83 patients, most often during a stroke
Timnou Bekouti Jean, Ravakiniaina Ranaivosoa Mialy, Ateba Ateba Nelly Stella, Tsague Kegni Hermann, Rambolarimanana Mansh, Ndobo Julia Valérie, Imbey Eheth Levy, Maury Philippe, Diawara Alpha, Roynard Jean Louis, Boombhi Jerome Hilaire   +10 more
wiley   +1 more source

Use of Andexanet Alfa for Factor Xa Inhibitor Reversal in US Verified Trauma Centers: A National Survey

Clinical and Applied Thrombosis/Hemostasis
Direct oral factor Xa inhibitors are replacing vitamin K-dependent antagonists as anticoagulation treatment in many clinical scenarios. Trauma centers are noting an increase in patients presenting on these medications.
Charles Fasanya MD, FRCS FACS, Abenámar Arrillaga MD FACS FCCP, Catherine Caronia MD, MBA, Lauren Rothburd BS, Tenzing Japhe BA, Younghee Hahn BS, Paul Joseph BS, Dajana Reci BA, Patricia Eckardt PhD, RN, FAAN   +8 more
doaj   +1 more source

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, EarlyView.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source

Invalid Nucleic Acid Test Results May Limit Deceased Donor Organ Utilization

Transplant Infectious Disease, EarlyView.
Rare instances occur in which discriminatory NAT results cannot be resolved in deceased organ donor cases. When these events occur the impact on organ donation can be substantial. ABSTRACT Background Nucleic acid testing (NAT) is essential for detecting transmissible viral infections in deceased organ donors and guiding safe organ allocation.
Sara Dionne, Hillary Akana, Kaitlin Logue, Brenden O'Neale, Chris Curran, Sean VanSlyck   +5 more
wiley   +1 more source

Willingness to Pay for the Preservation of Lo Go - Xa Mat National Park in Vietnam [PDF]

Lo Go - Xa Mat National Park has great value in terms of biodiversity but preserving the park is a great challenge for the Vietnamese government. This study estimated the willingness to pay of households to preserve Lo Go - Xa Mat National Park, using ...
Nguyen Thi Y Ly, Dang Le Hoa
core  

New factor Xa inhibitors based on 1,2,3,4-tetrahydroquinoline developed by molecular modelling

Factor Xa is a serine protease representing a crucial element in the coagulation process and an attractive target for anticoagulant therapy. At the present time there are several chemical classes of factor Xa inhibitors with proven activity. Furthermore,
Krysin M., Ilin I., Sulimov V., Potapov A., Sapronova L., Ataullakhanov F., Zubkov F., Kutov D., Shikhaliev K., Sulimov A., Lipets E.   +10 more
core   +1 more source

Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage. [PDF]

BACKGROUND Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion ...
Kallmuenzer, B, Sharma, M, Toni, Danilo, Ekholm, Ella, Lang, W, Seiffge, David J., Bereczki, D, Robinson, Thompson G., Connolly, Stuart J., Lindgren, Arne G, Crowther, Mark, Lang, Wilfried, Gumbinger, C, Czlonkowska, A, Demchuk, Andrew M, Himmelmann, Anders, Veltkamp, Roland, Taylor, A, Verhamme, P, Tsivgoulis, G, Shoamanesh, A, Sandset, Else Charlotte, Cohen, AT, Ladenvall, P, Ekholm, E, Law, Andrew, Verhamme, Peter, Demchuk, Andrew M., Connolly, SJ, Knutsson, Mikael, Taylor, Amanda, Tanne, David, Robinson, Thompson G, Poli, Sven, Xu, LZ, Coutinho, Jonathan M, Xu, Lizhen, Molina, Carlos A, Law, A, Tsiplova, K, Himmelmann, A, Bereczki, Daniel, Roine, Risto O, Milling, TJ, Lemmens, R, Seiffge, David J, Roine, RO, Gumbinger, Christoph, Amarenco, Pierre, Seiffge, DJ, Sandset, EC, Tanne, D, Toni, D, Cohen, Alexander T, Christensen, H, Beyer-Westendorf, Jan, Kallmünzer, Bernd, Knutsson, M, Lindgren, Arne G., Roine, Risto O., Coutinho, Jonathan M., Sharma, Mukul, Molina, CA, Ladenvall, Per, Shoamanesh, Ashkan, Robinson, TG, Cohen, Alexander T., Connolly, Stuart J, Lemmens, Robin, Middeldorp, Saskia, Demchuk, AM, Karyakina, T, Tedim Cruz, V, Coutinho, JM, Veltkamp, R, ANNEXA-I Investigators, Mikulik, Robert, Christensen, Hanne, Lindgren, AG, Middeldorp, S, Amarenco, P, Becattini, Cecilia, Beyer Westendorf, J, Crowther, M, Mikulik, R, Tsiplova, Kate, Karyakina, Tetyana, Członkowska, Anna, Tedim-Cruz, Vitor, Tsivgoulis, Georgios, Milling, Truman John, Molina, Carlos A., Poli, S   +92 more
core   +1 more source

Normal thromboelastography with a markedly prolonged activated partial thromboplastin time in severe prekallikrein deficiency: Implications for perioperative hemostatic assessment

Transfusion, EarlyView.
Abstract Background Prekallikrein (PK) deficiency is a rare contact factor deficiency that can markedly prolong the activated partial thromboplastin time (aPTT) without a bleeding phenotype. Because viscoelastic hemostatic assays also rely on contact activation, their behavior in severe PK deficiency is relevant to perioperative evaluation of isolated ...
Jeremy W. Jacobs, Anton Matafonov, Patricia G. Baxter, Qiufang Cheng, Garrett S. Booth, Deva Sharma, Benjamin F. Tillman, David Gailani   +7 more
wiley   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, Volume 101, Issue 10, Page 2632-2651, October 2026.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Factor Xa inhibitors in hemodialysis: OK-for now! [PDF]

Proc (Bayl Univ Med Cent), 2023
Banchs JE.
europepmc   +1 more source