Results 91 to 100 of about 17,264 (156)

Factor Xa inhibitors in hemodialysis: OK-for now! [PDF]

Proc (Bayl Univ Med Cent), 2023
Banchs JE.
europepmc   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, Volume 183, Issue 22, Page 6607-6626, November 2026.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

ZmMS1 coordinates ROS homeostasis, lipid allocation, and male fertility for maize breeding applications

Journal of Integrative Plant Biology, Volume 68, Issue 11, Page 4030-4051, November 2026.
The redox‐sensitive transcriptional repressor ZmMS1 coordinates reactive oxygen species homeostasis and lipid allocation for pollen exine and anther cuticle formation. Loss or precocious expression of ZmMS1 causes male sterility. Constitutive overexpression induces dwarfism and semi‐sterility. These findings enable flexible maize male‐sterility systems
Quancan Hou, Xueli An, Zhenying Dong, Biao Ma, Suowei Wu, Ke Xie, Ziwen Li, Tingwei Yan, Yilin Jiang, Taotao Zhu, Bin Ma, Lina Zhao, Yan Long, Xiangyuan Wan   +13 more
wiley   +1 more source

Extending the Farquhar–von Caemmerer–Berry photosynthesis model to account for various photorespiratory bypasses

New Phytologist, Volume 252, Issue 3, Page 1327-1342, November 2026.
We extend a widely used C3‐photosynthesis model to account for various photorespiratory bypasses, thereby, providing a useful resource and framework that enforces future novel bypass work and scrutinize if the results go counter to theory. Our model analyses show that of the 17 published bypass pathways, full‐decarboxylating bypasses (that have been ...
Xinyou Yin, Kaining Jin, Guoxin Chen, Tiegang Lu   +3 more
wiley   +1 more source

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, Volume 24, Issue 11, Page 5616-5630, November 2026.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source

Clinical utility of rivaroxaban in stroke prevention associated with nonvalvular atrial fibrillation – patient considerations

Journal of Blood Medicine, 2014
Ingo Ahrens, Christoph Bode Heart Center, University of Freiburg, Department of Cardiology and Angiology I, Freiburg, Germany Abstract: The direct factor Xa inhibitor rivaroxaban was the first within the group of orally available direct factor Xa ...
Ahrens I, Bode C
doaj  

Subsequent Thromboembolic and Bleeding Events in Patients With Major Bleeding While on Factor Xa Inhibitors. [PDF]

Circ Rep
Suzuki T, Yasaka M, Wada F, Ide R, Suzuki K, Kohsaka S.   +5 more
europepmc   +1 more source

Safety Pharmacology, Toxicokinetics and Pharmacodynamics of VMX-C001, an Intravenous Bypassing Agent for Factor Xa Inhibitors, in Animal Models. [PDF]

Pharmaceutics
Verhoef D, Short G, Gomes T, Groen K, Spronk H, Ohrstrom J, Reitsma PH.   +6 more
europepmc   +1 more source

Residue‑resolved dynamically averaged interaction analysis of direct factor Xa inhibitors by MD‑FMO combination calculations. [PDF]

J Comput Aided Mol Des
Yoshine R, Hirano Y, Doi H, Kitahara S, Akisawa K, Okuwaki K, Yamamoto E, Yasuoka K, Mochizuki Y.   +8 more
europepmc   +1 more source

Kidney injury associated with direct oral anticoagulants: a comparative study of direct thrombin inhibitors and factor Xa inhibitors based on literature and database analysis. [PDF]

Ren Fail
Chen S, Shi C, Li X, Wang X, Guo R, Wu T.   +5 more
europepmc   +1 more source