Results 91 to 100 of about 18,017 (247)

Comparison of effectiveness and safety between uninterrupted direct oral anticoagulants with and without switching to dabigatran in atrial fibrillation ablation

Journal of Arrhythmia, 2020
Introduction Recent studies have demonstrated the feasibility of uninterrupted direct oral anticoagulants (DOACs) with a temporary switch to dabigatran (“dabigatran bridge”) for atrial fibrillation (AF) ablation.
Masahide Harada, Yuji Motoike, Yoshihiro Nomura, Asuka Nishimura, Masayuki Koshikawa, Kazuhiro Murayama, Yoshiharu Ohno, Eiichi Watanabe, Hideo Izawa, Yukio Ozaki   +9 more
doaj   +1 more source

Do We Really Know How to Manage Anticoagulated Patients for Periodontal Nonsurgical Therapy? An Observational Cohort Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives The aim of this work is to assess and compare the impact of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKA) during and immediately after periodontal nonsurgical therapy. Materials and Methods A prospective observational cohort study was conducted with patients who presented a history of cardiovascular disease ...
F. Berton, A. Rapani, F. Costantinides, V. Nicolin, D. Cuhureanu, R. Di Lenarda   +5 more
wiley   +1 more source

Reversal Agents for the Direct Factor Xa Inhibitors: Biochemical Mechanisms of Current and Newly Emerging Therapies

, 2020
The direct oral anticoagulants targeting coagulation factor Xa or thrombin are widelyused as alternatives to vitamin K antagonists in the management of venous thromboembolismand nonvalvular atrial fibrillation.
Mark Schreuder, Pieter H. Reitsma, Schreuder, M., Reitsma, P.H., Bos, M.H.A., Mettine H. A. Bos   +5 more
core   +1 more source

Design and Implementation of an Automated Interpretation Algorithm for Lupus Anticoagulant Functional Testing

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Lupus anticoagulant (LA) testing is essential, albeit complex, in the laboratory diagnosis of antiphospholipid syndrome (APS). Given the multi‐step workflow and the variability introduced by anticoagulant therapy, reagent differences, and interpretive approaches, result interpretation requires expert evaluation.
Chiara Novelli, Arianna Gatti, Flora Ierna, Elena Riccardi, Irene Cuppari   +4 more
wiley   +1 more source

Deep vein thrombosis prophylaxis in patients who undergo knee arthroscopy: a systematic review

Knee Surgery & Related Research
Background Knee arthroscopy is one of the most common procedures performed by orthopedic surgeons. A potentially life-threatening complication following this procedure is deep vein thrombosis (DVT). DVT prophylaxis can be obtained both mechanically (e.g.,
Udit Dave, Emma G. Lewis, Victoria K. Ierulli, Shreya M. Saraf, Mary K. Mulcahey   +4 more
doaj   +1 more source

How I Investigate Borderline Prolonged aPTT: An Integrated Laboratory Approach to Mixing Studies and Factor Analysis

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Borderline prolongation of routine clotting assays—particularly the activated partial thromboplastin time (aPTT)—is a common interpretative challenge in laboratory hematology. These reproducible but mildly prolonged results often lie just beyond the upper reference limit and can trigger unnecessary follow‐up, delays, or misinterpretation ...
Nikolaos Androulakis, Eleni Nioti, Antonios Dilintas, Christina Kalpadakis   +3 more
wiley   +1 more source

ZmMS1 coordinates ROS homeostasis, lipid allocation, and male fertility for maize breeding applications

Journal of Integrative Plant Biology, EarlyView.
The redox‐sensitive transcriptional repressor ZmMS1 coordinates reactive oxygen species homeostasis and lipid allocation for pollen exine and anther cuticle formation. Loss or precocious expression of ZmMS1 causes male sterility. Constitutive overexpression induces dwarfism and semi‐sterility. These findings enable flexible maize male‐sterility systems
Quancan Hou, Xueli An, Zhenying Dong, Biao Ma, Suowei Wu, Ke Xie, Ziwen Li, Tingwei Yan, Yilin Jiang, Taotao Zhu, Bin Ma, Lina Zhao, Yan Long, Xiangyuan Wan   +13 more
wiley   +1 more source

Changes in Internal Structure and Dynamics upon Binding Stabilise the Nematode Anticoagulant NAPc2

Biomolecules
Abnormal blood coagulation is a major health problem and natural anticoagulants from blood-feeding organisms have been investigated as novel therapeutics.
Elaine Woodward, Brendan M. Duggan
doaj   +1 more source

Activated prothrombin complex concentrate to reverse the factor Xa inhibitor (apixaban) effect before emergency surgery: a case series

Journal of Medical Case Reports, 2018
Background The lack of an antidote against factor Xa inhibitors in case of major bleeding or need for urgent surgery is a concern to clinicians. Guidelines on managing major bleeding in patients under anticoagulation with a factor Xa inhibitor suggest ...
Nina Haagenrud Schultz, Runar Lundblad, Pål Andre Holme   +2 more
doaj   +1 more source

Attachment insecurity and psychological (mal)adjustment in older adults: The longitudinal role of fear of self‐compassion

Psychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Objectives Insecure attachment has been suggested to precede and perpetuate fear of self‐compassion, with a negative impact on mental health. However, this evidence was obtained using general‐age samples and cross‐sectional designs. Our objective was to, in an older adult sample, analyse longitudinally the indirect effect of fear of self ...
Lúcia Tavares, Paula Vagos, Ana Xavier
wiley   +1 more source