Results 81 to 90 of about 38,154 (222)

Variability in ACT Response to Standard UFH Bolus During PCI: A Prospective Study on Determinants of Subtherapeutic Anticoagulation

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Unfractionated heparin (UFH) remains the standard anticoagulant during percutaneous coronary intervention (PCI), with guidelines recommending a target activated clotting time (ACT) of ≥250 s. However, despite receiving a standardized bolus dose, many patients fail to achieve this target.
Manh Cuong Vu, Antonin Trimaille, Amandine Granier, Adrien Carmona, Anis Elidrissi, Marion Kibler, Laurence Jesel, Patrick Ohlmann, Laurent Sattler, Olivier Morel   +9 more
wiley   +1 more source

Is There an Alternative Oral Anticoagulation to Vitamin-K-Antagonists for Patients with Mechanical Aortic Valve Replacement? – A Literature Review

Cardiology and Therapy
Current guidelines exclusively recommend vitamin-K-antagonists (VKA) as anticoagulation for patients after mechanical aortic valve replacement due to the increased postoperative risk of valve thrombosis and thrombo-embolism.
Stephen Gerfer, Thorsten Wahlers, Elmar Kuhn   +2 more
doaj   +1 more source

Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer. [PDF]

, 2014
Preventing breast cancer is an effective strategy for reducing breast cancer deaths. The purpose of chemoprevention (also termed preventive therapy) is to reduce cancer incidence by use of natural, synthetic, or biological agents.
Brown, Powel H, Litzenburger, Beate C
core   +1 more source

Waste activated sludge high‐rate treatment of septage: Biodegradability studies and contact phase trials towards a cleaner environment

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract The waste activated sludge high‐rate (WASHR) process, developed in our previous study, is used for septic wastewater treatment. This high‐rate contact stabilization pre‐treatment uses typical waste streams found in wastewater treatment plants to reduce a portion of the loadings on the main treatment trains.
Arman Shirali, Melody Blythe Johnson, Mehrab Mehrvar   +2 more
wiley   +1 more source

Assessing Safety of Direct Thrombin Inhibitors, Direct Factor Xa Inhibitors and Vitamin K Antagonists in Patients with Atrial Fibrillation: A Nation-Wide Propensity Score Matched Cohort from Sweden

Clinical Epidemiology, 2020
Marie Linder,1 Anastasia Iliadou Nyman,2,3 Helle Kieler,1 Bengt Danielsson,2 Natalia Borg,2 Marcus Gry,2 Julius Collin2 1Centre for Pharmacoepidemiology, Karolinska Institutet, T2, Karolinska University Hospital, Stockholm, Sweden; 2The National Board of
Linder M, Iliadou Nyman A, Kieler H, Danielsson B, Borg N, Gry M, Collin J   +6 more
doaj  

A Perspective of Coagulation Dysfunction in Multiple Sclerosis and in Experimental Allergic Encephalomyelitis [PDF]

, 2018
A key role of both coagulation and vascular thrombosis has been reported since the first descriptions of multiple sclerosis (MS). Subsequently, the observation of a close concordance between perivascular fibrin(ogen) deposition and the occurrence of ...
Adams, Adams, Akassoglou, Akassoglou, Akenami, Akenami, Albright, Alizadeh, Alonso, Amor, Antoniak, Beggs, Bidot, Bitsch, Boesen, Brkic, Bronstein, Brunetti, Castellino, Cesarman-Maus, Chapman, Chelmicka-Szorc, Claudio, Compston, Coughlin, Cuzner, Danø, Davalos, Davalos, Davidson, Davie, De Luca, Dekaban, Deschepper, Donovan, East, Ed Rainger, Engelmann, Esmon, Esmon, Fan, Fan, Farber, Feldman, Ferguson, Festoff, Field, Fiorini, Flick, Fog, Friedman, Garcia-Monco, García, Garg, Genc, Gloor, Griffin, Griffin, Guenther, Gveric, Göbel, Göbel, Göbel, Hafler, Han, Horstman, Huszak, Inaba, Inoue, Iong, Jacob, Jones, Kalaria, Kirichuk, Kirk, Kirk, Knauer, Koudriavtseva, Koudriavtseva, Koudriavtseva, Koudriavtseva, Kreutzberg, Kuhlmann, Kwon, Lane, Langer, Lassmann, Lassmann, Lassmann, Lesny, Liddelow, Lider, Lin, Lin, Lock, Lu, Mahmood, Mandoj, Marik, Mechelli, Miranda, Moll, Murray, Park, Parsons, Paterson, Perez, Persson, Persson, Petersen, Phillips, Pike, Plantone, Plumb, Putnam, Putnam, Rand, Reese, Reinhard, Roizin, Ryu, Ryu, Saberi, Savitky, Seeds, Seeds, Sheremata, Simón, Smith, Sobel, Soon, Sotnikov, Spadaro, Starossom, Starossom, Stavrou, Stolz, Teesalu, Tennent, Ugarova, Uzawa, van der Poll, Varga, Verrall, Wachowicz, Wakefield, Weisel, Whitlock, Wittinghofer, Wolter, Wright, Xue, Yadav, Yamaji, Yates, Yuksel, Zhang, Ziliotto, Zivadinov   +158 more
core   +1 more source

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

Non-canonical proteolytic activation of human prothrombin by subtilisin from Bacillus subtilis may shift the procoagulant\ue2\u80\u93anticoagulant equilibrium toward thrombosis [PDF]

, 2017
Blood coagulation is a finely regulated physiological process culminating with the factor Xa (FXa)-mediated conversion of the prothrombin (ProT) zymogen to active -thrombin (T).
Acquasaliente, Laura, Artusi, Ilaria, De Filippis, Vincenzo, Frasson, Roberta, Peterle, Daniele, Pontarollo, Giulia   +5 more
core   +1 more source

Nutritional, phytochemical, and potential health benefits of Monostroma spp.: A systematic review

Food Biomacromolecules, EarlyView.
Abstract Monostroma spp., belonging to the green seaweed, has been known to be health‐promoting food items as prophylactic agents worldwide. It has shown wide arrays of bioactivities for the prevention and treatment of various diseases. A total of 47 articles were selected to review following the Preferred Reporting Items for Systematic reviews and ...
Md Shariful Islam
wiley   +1 more source

Function of the Signal Peptide and N- and C-terminal Propeptides in the Leucine Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e [PDF]

, 2004
The leucine aminopeptidase from Aeromonas proteolytica (also known as Vibrio proteolyticus) (AAP) is a metalloenzyme with broad substrate specificity. The open reading frame (ORF) for AAP encodes a 54 kDa enzyme, however, the extracellular enzyme has a ...
Bzymek, Krzysztof P., Campbell, Heidi, Chen, Guanjing, D\u27Souza, Ventris M., Holz, Richard C., Mitchell, Alice   +5 more
core   +1 more source