Results 221 to 230 of about 15,476,282 (336)

A model of zymogen factor XII: insights into protease activation. [PDF]

Blood Adv
Shamanaev A, Ma Y, Ponczek MB, Sun MF, Cheng Q, Dickeson SK, McCarty OJT, Emsley J, Mohammed BM, Gailani D.   +9 more
europepmc   +1 more source

A phase I, first-in-human, randomized dose-escalation study of anti-activated factor XII monoclonal antibody garadacimab. [PDF]

Clin Transl Sci, 2022
McKenzie A, Roberts A, Malandkar S, Feuersenger H, Panousis C, Pawaskar D.   +5 more
europepmc   +1 more source

Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity.

Journal of Medicinal Chemistry, 2017
S. Middendorp, Jonas Wilbs, Claudia Quarroz, S. Calzavarini, A. Angelillo-Scherrer, C. Heinis   +5 more
semanticscholar   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

Advanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun, Hang Xian, Yunxin Shi, Taotan Yang, Hongyan Shuai, Wenchao Hu, Siying Fei, Miao Xu, Taoyuan Yang, Ruilong Xia, Ting Wen, Fengting Zhu, Yan Fu, Yang Li, Wei Xia, Ran Qian, Yuanying Liu, Zhicheng Tian, Lamei Li, Qian Zhou, Lize Xiong, Rui Cong, Ceng Luo, Shengxi Wu, Xiafeng Shen, Xin Yu, Rou‐Gang Xie, Changgeng Peng   +27 more
wiley   +1 more source

Lipopolysaccharide supramolecular organization regulates the activation of coagulation factor XII. [PDF]

Biochim Biophys Acta Biomembr
Lira AL, Liu T, Aslan JE, Puy C, McCarty OJT.   +4 more
europepmc   +1 more source

Polyphosphate-induced thrombosis in mice is factor XII dependent and is attenuated by histidine-rich glycoprotein. [PDF]

Blood Adv, 2021
Malik RA, Zhou J, Fredenburgh JC, Truong TK, Crosby JR, Revenko AS, Weitz JI.   +6 more
europepmc   +1 more source

Design of Optical Transducer for Recognition of Biomolecular Interactions between Bacterial Lipopolysaccharides and Amino Acids

Advanced Science, EarlyView.
A deep comprehension of biomolecular phenomena at interfaces is significant with their fundamental and practical importance. Our experimental and theoretical investigations reveal that specific amino acids (glutamic acid and aspartic acid) exhibit an orientational coupling with liquid crystals, which can recognize and optically report the interfacial ...
Yena Choi, Sangmin Lee, Jin‐Kang Choi, Hyunsoo Han, Yeongseon Choi, Jun‐Hyung Im, Hyein Kim, Sangmin Jeon, Minjae Lee, Chang Yun Son, Young‐Ki Kim   +10 more
wiley   +1 more source

Genetic analysis of a pedigree with hereditary coagulation factor XII deficiency. [PDF]

Ann Hematol
Fang W, Chen B, Zou A, Xu F, Qin L, Yang L, Wang M, Zhou X.   +7 more
europepmc   +1 more source

Polyphosphate expression by cancer cell extracellular vesicles mediates binding of factor XII and contact activation. [PDF]

Blood Adv, 2021
Shim YJ, Chatterjee V, Swaidani S, Alluri RK, Kundu S, Merkulova A, Angelini D, You D, Whitney SA, Feener EP, Barnard J, Schmaier AH, Khorana AA, McCrae KR.   +13 more
europepmc   +1 more source

Factor XII Inactivation [PDF]

, 2020
openaire   +1 more source