Results 291 to 300 of about 15,476,282 (336)
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Experimental and clinical endocrinology & diabetes, 2019
Background In diabetic retinopathy (DR), neutrophil extracellular traps (NET) and kallikrein-kinin system are considered as contributing factors. However, the detail activation mechanisms has not been fully understood.
D. Song +6 more
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Background In diabetic retinopathy (DR), neutrophil extracellular traps (NET) and kallikrein-kinin system are considered as contributing factors. However, the detail activation mechanisms has not been fully understood.
D. Song +6 more
semanticscholar +1 more source
Assay of total factor XII and of activated factor XII in plasma with a chromogenic substrate
Thrombosis Research, 1979Abstract The chromogenic substrate H-D-Pro-Phe-Arg-pNA (S-2302 KABI) is split by plasma kallikrein and by plasmin. Since kallikrein is activated from its precursor prekallikrein by the action of active factor XII, a photometric assay method for this factor was developed.
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Factor XII Osaka: Abnormal factor XII with partially defective prekallikrein cleavage activity
Thrombosis and Haemostasis, 2011SummaryA healthy Japanese male had reduced factor XII (FXII) activity (35%) in contrast to normal antigen levels (81%). The F12 of this proband had a 9775G to C mutation in exon 10 and an 11276G to A mutation in exon 13 that resulted in two amino acid substitutions of Ala324Pro (GCG→CCG) in the proline-rich connecting region and Gly531Glu (GGG→GAG ...
Kenji, Iijima +6 more
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[Factor XII (HAGEMAN FACTOR)].
Folia haematologica (Leipzig, Germany : 1928), 1978The discovery of factor XII (Hageman factor), the attempts of characterizing it, the knowledge of its presence of absence in the various vertebrate classes are represented in a survey and recent opinions of molecular biology about its structure and composition are discussed.
F, Kase +3 more
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British Journal of Haematology, 2000
Antibodies to factor XII (FXII) have previously been identified in some patients who were lupus anti‐coagulant‐positive. The relationship between these antibodies and FXII levels appeared to be variable. The aim of the present study was to confirm the presence of antibodies to FXII in patients with well characterized antiphospholipid syndrome (APS) and
D W, Jones +4 more
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Antibodies to factor XII (FXII) have previously been identified in some patients who were lupus anti‐coagulant‐positive. The relationship between these antibodies and FXII levels appeared to be variable. The aim of the present study was to confirm the presence of antibodies to FXII in patients with well characterized antiphospholipid syndrome (APS) and
D W, Jones +4 more
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Behçet's syndrome and factor XII deficiency
Clinical Rheumatology, 1992Several mechanisms have been proposed to explain thrombotic tendency in Behçet's syndrome. We report the case of a 43-year old woman presenting retinal-vein thrombosis, factor XII deficiency and Behçet's syndrome. This kind of association has thus far never been reported. Factor XII deficiency is known to possibly induce various types of thrombosis and
P, Disdier +4 more
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Factor XII deficiency and cardiopulmonary bypass
Perfusion, 1995Factor XII initiates the intrinsic coagulation cascade and may affect the fibrinolytic system. Routine coagulation tests used during cardiopulmonary bypass (CPB) are abnormal in factor-XII-deficient patients and are useless for monitoring anticoagulation in these patients. A factor-XII-deficient patient requiring CPB is described. The baseline celite
M, Wallock, C, Arentzen, J, Perkins
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Structural and Functional Characterization of Factor XII
Seminars in Thrombosis and Hemostasis, 1987In this article we have reviewed the current knowledge regarding the involvement of Factor XII in contact activation. Clearly in the past decade an overwhelming amount of data and hypotheses have been published regarding the central role of this zymogen in the initiation and further propagation of contact activation reactions. Therefore we feel that it
G, Tans, J, Rosing
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Bilten za hematologiju i transfuziju, 1985
The work presents classical form and variant of F XII deficiency. Although a rare disorder, F XII deficiency can lead to bleeding, particularly after injuries and surgeries. Further laboratory investigation of patients with pathological APTT is required.
C, Vera +4 more
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The work presents classical form and variant of F XII deficiency. Although a rare disorder, F XII deficiency can lead to bleeding, particularly after injuries and surgeries. Further laboratory investigation of patients with pathological APTT is required.
C, Vera +4 more
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New Families with Factor XII Deficiency
Thrombosis and Haemostasis, 1970SummaryHereditary factor XII deficiency is reported in 2 unrelated Norwegian families.Case 1 was a 50 year old female, who was investigated because of a subcutaneous hematoma of unexplained cause. She had bruised easily, but neither she nor members of her family had suffered from definite and marked bleeding tendency.
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