Results 131 to 140 of about 410,939 (360)
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
On permutation polynomials over finite fields
A polynomial f over a finite field F is called a permutation polynomial if the mapping F→F defined by f is one-to-one. In this paper we consider the problem of characterizing permutation polynomials; that is, we seek conditions on the coefficients of a ...
R. A. Mollin, C. Small
doaj +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Some factorizations of numbers of the form 2ⁿ±1 [PDF]
Raphael M. Robinson
openalex +1 more source
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
On matrices associated to prime factorization of odd integers
In this paper we introduce in section 5 integral matrices M(n) for any factorization of an odd integer n into r distinct odd primes. The matrices appear in several versions according to a parameter ρ∈[0,1], they have size 2r×2r and their rank satisfies e.
T. Bier
doaj +1 more source