Results 71 to 80 of about 14,368 (309)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Characterizing Variability of Modular Brain Connectivity with Constrained Principal Component Analysis. [PDF]

open access: yesPLoS ONE, 2016
Characterizing the variability of resting-state functional brain connectivity across subjects and/or over time has recently attracted much attention.
Jun-Ichiro Hirayama   +4 more
doaj   +1 more source

On theLU factorization ofM-matrices

open access: yesNumerische Mathematik, 1981
In this paper, we give in Theorem 1 a characterization, based on graph theory, of when anM-matrixA admits anLU factorization intoM-matrices, whereL is a nonsingular lower triangularM-matrix andU is an upper triangularM-matrix. This result generalizes earlier factorization results of Fiedler and Ptak (1962) and Kuo (1977). As a consequence of Theorem 1,
VARGA, R.S., Cai, D.Y.
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Bidiagonal Factorizations of Filbert and Lilbert Matrices

open access: yesAxioms
Extensions of Filbert and Lilbert matrices are addressed in this work. They are reciprocal Hankel matrices based on Fibonacci and Lucas numbers, respectively, and both are related to Hilbert matrices.
Yasmina Khiar   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Evaluation of Partial Factorization for Reduction of Finite Element Matrices

open access: yesEngineering Transactions, 2017
In this paper, we present the concept of Partial Factorization [1] And discuss its possible applications to the Finite Element method. We consider: (1) reduction of the element tangent matrix, which is particularly important for mixed/enhanced elements ...
Pawel JARZĘBSKI, Krzysztof WIŚNIEWSKI
doaj   +1 more source

Lower bounds for some factorable matrices [PDF]

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2006
We determine the lower bounds for classes of Rhaly matrices, considered as bounded linear operators on ℓ p . We improve on and provide correct proofs of the results of the first author (1990).
B. E. Rhoades, Pali Sen
openaire   +2 more sources

Cholesky Factorization of Matrices [PDF]

open access: yes, 2020
Cholesky factorization is a type of matrix factorization which is used for solving system of linear equations. In this paper, we will study the factorization of real positive definite matrices by using Cholesky factorization.
Khin Myo Aye
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

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