Results 91 to 100 of about 14,368 (309)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Fast Computation for Square Matrix Factorization
ComputersIn this work, we discuss a method for the QR-factorization of N×N matrices where N≥3 which is based on transformations which are called discrete signal-induced heap transformations (DsiHTs). These transformations are generated by given signals and can be
Artyom M. Grigoryan
doaj +1 more source
Solution to the General Inner-Outer and Spectral Factorization Problems
, 1998 In this paper we solve two open problems in linear system theory: the computation of the spectral and inner-outer factorizations of a rational matrix G in the most general setting.
Varga, A., Oara, C.
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Minor Prime Factorization for n-D Polynomial Matrices over Arbitrary Coefficient Field
Complexity, 2018 In this paper, we investigate two classes of multivariate (n-D) polynomial matrices whose coefficient field is arbitrary and the greatest common divisor of maximal order minors satisfy certain condition.
Jinwang Liu, Dongmei Li, Licui Zheng
doaj +1 more source
Factorization of generalized γ-generating matrices [PDF]
Journal of Mathematical Sciences, 2018 The class of \(\gamma\)-generating matrices and its subclasses of regular and singular \(\gamma\)-generating matrices were introduced in [\textit{D. Z. Arov}, J. Sov. Math. 52, No. 6, 3487--3491 (1990; Zbl 0718.41004); translation from Teor. Funkts., Funkts. Anal. Prilozh.
openaire +3 more sources
Using underapproximations for sparse nonnegative matrix factorization [PDF]
Nonnegative Matrix Factorization (NMF) has gathered a lot of attention in the last decade and has been successfully applied in numerous applications.
GILLIS, Nicolas, GLINEUR, François
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Holomorphic Factorization of Matrices of Polynomials [PDF]
, 1999 This paper considers some work done by the author and Catlin [CD1,CD2,CD3] concerning positivity conditions for bihomogeneous polynomials and metrics on bundles over certain complex manifolds. It presents a simpler proof of a special case of the main result in [CD3], providing also a self-contained proof of a generalization of the main result from [CD1]
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source