Results 81 to 90 of about 165,987,094 (304)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Computation of General Inner-Outer and Spectral Factorizations [PDF]
In this paper, we solve two problems in linear systems theory: the computation of the inner-outer and spectral factorizations of a continuous-time system considered in the most general setting.
Varga, A., Oara, C.
core
Directional clustering through matrix factorization [PDF]
This paper deals with a clustering problem where feature vectors are clustered depending on the angle between feature vectors, that is, feature vectors are grouped together if they point roughly in the same direction.
Blumensath, Thomas
core +1 more source
Vector-exponential time-series modeling for polynomial J-spectral factorization
An iterative algorithm to perform the J-spectral factorization of a para-Hermitian matrix is presented. The algorithm proceeds by computing a special kernel representation of an interpolant for a sequence of points and associated directions determined ...
Pendharkar, Ishan +2 more
core +1 more source
Lower bounds for some factorable matrices [PDF]
We determine the lower bounds for classes of Rhaly matrices, considered as bounded linear operators on ℓ p . We improve on and provide correct proofs of the results of the first author (1990).
B. E. Rhoades, Pali Sen
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Traditional wet experiments to identify drug–target interactions (DTIs) are costly and time consuming. Therefore, machine learning-based methods are commonly used to speed up the identification process.
Junjun Zhang, Tingfeng Zeng
doaj +1 more source
Factorization identities and algebraic Bethe ansatz for D 2 2 $$ {D}_2^{(2)} $$ models
We express D 2 2 $$ {D}_2^{(2)} $$ transfer matrices as products of A 1 1 $$ {A}_1^{(1)} $$ transfer matrices, for both closed and open spin chains. We use these relations, which we call factorization identities, to solve the models by algebraic Bethe ...
Rafael I. Nepomechie, Ana L. Retore
doaj +1 more source
Holomorphic Factorization of Matrices of Polynomials [PDF]
This paper considers some work done by the author and Catlin [CD1,CD2,CD3] concerning positivity conditions for bihomogeneous polynomials and metrics on bundles over certain complex manifolds. It presents a simpler proof of a special case of the main result in [CD3], providing also a self-contained proof of a generalization of the main result from [CD1]
openaire +2 more sources

