Results 241 to 250 of about 15,541,552 (290)

Organizational Factors, Beliefs, Caring Behavior, and Quality of Nursing Work Life Among ICU Nurses: A Carolina Care-Informed Structural Model. [PDF]

Nurs Res Pract
Sukartini T, Dewi YS, Mariyanti H, Ramoo V, Kanchana G, Al-Faruq MF, Hamidah AN, Raihanatu Y, Syahri A.   +8 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Identifying risk factors associated with postpartum depression: a retrospective case-control study. [PDF]

BMC Pregnancy Childbirth
Volz R, Coenen VA, Baldermann JC, Döbrössy MD.   +3 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Perspectives on influential factors for the adoption of circular economy practices. [PDF]

Circ Econ Sustain
Dutra CJC.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Resting Heart Rate Association with Cardiovascular Morbidity and Mortality and All-Cause Mortality According to Cluster of Cardiovascular Risk Factors-A Prospective Cohort Study with More than 20 Years of Follow-Up. [PDF]

J Clin Med
Carbayo-Herencia JA, Artigao Ródenas LM, Simarro-Rueda M, Molina-Escribano F, Navarro-Blazquez F, Gil-Guillén V, Banegas JR, Divisón Garrote JA.   +7 more
europepmc   +1 more source

Risk factors and methods of NSSI and suicide attempts among American Indian and Alaska native adolescents and young adults: A systematic review protocol. [PDF]

PLoS One
Sadath A, Zhang Y, Rudra PK, Farooq O, Draft D, Reay S.   +5 more
europepmc   +1 more source