Results 1 to 10 of about 470,578 (143)
A Transcriptomic Approach to the Recruitment of Venom Proteins in a Marine Annelid
Toxins, 2021 The growing number of known venomous marine invertebrates indicates that chemical warfare plays an important role in adapting to diversified ecological niches, even though it remains unclear how toxins fit into the evolutionary history of these animals ...
Ana P. Rodrigo +4 more
doaj +1 more source
Localization and Bioreactivity of Cysteine-Rich Secretions in the Marine Gastropod Nucella lapillus
Marine Drugs, 2021 Marine biodiversity has been yielding promising novel bioproducts from venomous animals. Despite the auspices of conotoxins, which originated the paradigmatic painkiller Prialt, the biotechnological potential of gastropod venoms remains to be explored ...
Mariaelena D’Ambrosio +4 more
doaj +1 more source
Gene Therapy in Cancer Treatment: Why Go Nano?
Pharmaceutics, 2020 The proposal of gene therapy to tackle cancer development has been instrumental for the development of novel approaches and strategies to fight this disease, but the efficacy of the proposed strategies has still fallen short of delivering the full ...
Catarina Roma-Rodrigues +3 more
doaj +1 more source
Molecules, 2015 The majority of heterocycle compounds and typically common heterocycle fragments present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility and unique physicochemical properties, have poised them as true cornerstones ...
Pedro Martins +6 more
doaj +1 more source
Frontiers in Microbiology, 2020 The pyogenic streptococci group includes pathogenic species for humans and other animals and has been associated with enduring morbidity and high mortality. The main reason for the treatment failure of streptococcal infections is the increased resistance
Cinthia Alves-Barroco +4 more
doaj +1 more source
Gold Nanoparticles for Diagnostics: Advances towards Points of Care
Diagnostics, 2016 The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted developments in the exploration of biomolecular interactions with AuNP-containing systems, in particular for biomedical applications in diagnostics.
Mílton Cordeiro +4 more
doaj +1 more source
MicrobiologyOpen, 2019 Streptococcus dysgalactiae subsp. dysgalactiae (SDSD) is a major cause of bovine mastitis and has been regarded as an animal‐restricted pathogen, although rare infections have been described in humans.
Cinthia Alves‐Barroco +8 more
doaj +1 more source
Nanoparticles—Emerging Potential for Managing Leukemia and Lymphoma
Frontiers in Bioengineering and Biotechnology, 2017 Nanotechnology has become a powerful approach to improve the way we diagnose and treat cancer. In particular, nanoparticles (NPs) possess unique features for enhanced sensitivity and selectivity for earlier detection of circulating cancer biomarkers.
Raquel Vinhas +3 more
doaj +1 more source
Multiple Pathways to Homothallism in Closely Related Yeast Lineages in the Basidiomycota
mBio, 2021 Sexual reproduction is important for the biology of eukaryotes because it strongly impacts the dynamics of genetic variation. In fungi, although sexual reproduction is usually associated with the fusion between cells belonging to different individuals ...
Alexandra Cabrita +5 more
doaj +1 more source
Wheezing in infants: frequency, clinical characteristics and treatment [PDF]
, 2012 OBJECTIVE: To estimate the frequency and describe the clinical characteristics and respective treatments of previous history of wheezing. METHODS: Infants aged 6-23 months with upper respiratory tract complaints and reporting previous wheezing were ...
Amoedo, Ramon S. +10 more
core +2 more sources