Results 121 to 130 of about 8,880,978 (346)
Unleashing the Early Career Transition in Academic Medicine
Journal of Healthcare LeadershipDaryn H David Yale Child Study Center & Offices of Academic & Professional Development (OAPD) and Diversity, Equity, & Inclusion (ODEI), Yale School of Medicine, New Haven, CT, USACorrespondence: Daryn H David, Yale Child Study Center, Yale School of ...
David DH
doaj
ERNEST SOSA VE ENTELEKTÜEL ERDEMLER
Felsefe Dünyası, 2016 Modern/Çağdaş epistemolojinin kurucusu olarak kabul edilen çağdaş analitik filozoflardan Ernest Sosa, söz konusu epistemolojisinin en temel iki kavramından bir olan entelektüel erdem kavramını, temelcilik ve bağdaşımcılık arasındaki ‘ezeli’ sorunu ...
Kemal Batak
doaj
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Faculty Opinions recommendation of Auxin stimulates its own transport by shaping actin filaments.
, 2009 Clive Lloyd, Henrik Buschmann
openalex +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source