Results 121 to 130 of about 166,366,124 (299)
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
The Fate of the Humanities in the Public University [PDF]
The University of Maine Humanities Initiative IUMHI] seeks funding to support a keynote.lecture that will be part of its series of lectures and seminars in Spring 2012 that will be offered under the broad theme of The Contemporary Role of the Humanities.
University of Maine Humanities Initiative
core
The Welenrengnge Boat Model: Maritim Character Building Of Higher Education In Indonesia
This study is a cultural research using a descriptive qualitative design, namely Maritim character values in the script of Sawerigading Voyage to China is profoundly classified, interpreted, and described.
AB Takko Bandung
doaj
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Teaching for Prosperity? Preparing American Studies Students for the Job Market
This essay explores the challenges faced by American studies faculty and students in Denmark, specifically those preparing for careers in Danish-American relations outside academia.
Anne Mørk
doaj +1 more source
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Faculty Senate Minutes March 7, 2016
This item contains the agenda, minutes, and attachments for the Faculty Senate meeting on this date.
University of Arizona Faculty Senate
core

