Results 41 to 50 of about 12,747,404 (156)

Experimental co-infection of variant infectious bursal disease virus and fowl adenovirus serotype 4 increases mortality and reduces immune response in chickens

Veterinary Research, 2021
Infectious bursal disease virus (IBDV) and fowl adenovirus serotype 4 (FAdV-4) cause infectious bursal disease (IBD) and hydropericardium-hepatitis syndrome, respectively.
A-hui Xu, Lu Sun, Kai-hang Tu, Qing-yuan Teng, Jia Xue, Guo-zhong Zhang   +5 more
doaj   +1 more source

Genetic modification regulates pathogenicity of a fowl adenovirus 4 strain after cell line adaptation (genetic mutation in FAdV-4 lowered pathogenicity). [PDF]

Heliyon, 2023
Fowl adenovirus 4 (FAdV-4) is a major avian virus that induces fatal diseases in chicken such as, hydropericardium and hepatitis. The viral structure consists of hexon, penton, fiber-1, and fiber-2 which are associated with immunopathogenesis. In this study, we investigated the genetic modification of a FAdV-4 strain after continuous passages in a cell
Yeo JI, Lee R, Kim H, Ahn S, Park J, Sung HW.   +5 more
europepmc   +4 more sources

Fowl adenovirus serotype 4 enters leghorn male hepatocellular cells via the clathrin-mediated endocytosis pathway

Veterinary Research, 2023
Hepatitis-hydropericardium syndrome (HHS) induced by fowl adenovirus serotype-4 (FAdV-4) has caused large economic losses to the world poultry industry in recent years.
Ting Wang, Lizhen Wang, Wei Li, Xiaolan Hou, Wenchi Chang, Bo Wen, Shuizhong Han, Yan Chen, Xuefeng Qi, Jingyu Wang   +9 more
doaj   +1 more source

Gga-miR-30c-5p Enhances Apoptosis in Fowl Adenovirus Serotype 4-Infected Leghorn Male Hepatocellular Cells and Facilitates Viral Replication through Myeloid Cell Leukemia-1

Viruses, 2022
Fowl adenovirus serotype 4 (FAdV-4) is the primary causative agent responsible for the hepatitis-hydropericardium syndrome (HHS) in chickens, leading to considerable economic losses to stakeholders.
Areayi Haiyilati, Linyi Zhou, Jiaxin Li, Wei Li, Li Gao, Hong Cao, Yongqiang Wang, Xiaoqi Li, Shijun J. Zheng   +8 more
doaj   +1 more source

Characterization of Co-infection With Fowl Adenovirus Serotype 4 and 8a

Frontiers in Microbiology, 2021
Fowl adenoviruses (FAdVs), which are distributed worldwide, have caused considerable economic losses to poultry farms. Co-infection with FAdVs and other avian pathogens has been reported previously.
Jingyi Liu, Xinjin Shi, Lu Lv, Kai Wang, Zhiwei Yang, Yunzhang Li, Hongjun Chen   +6 more
doaj   +1 more source

Precise location of three novel linear epitopes using the generated monoclonal antibodies against the Knob domain of FAdV-4 surface structural protein, fiber1. [PDF]

Front Cell Infect Microbiol
BackgroundFowl adenovirus serotype 4 (FAdV-4) is the main pathogen of hepatitis-hydropericardium syndrome (HHS), which brings huge economic losses to the poultry industry worldwide.
Chai Y, Jin Q, Zhu R, Guo Z, Lu Q, Chai S, Xing Y, Han L, Xing G, Zhang G.   +9 more
europepmc   +2 more sources

Data_Sheet_1_TMT-based quantitative proteomics analysis reveals the role of Notch signaling in FAdV-4-infected LMH cell.doc

, 2022
Fowl adenovirus serotype 4 (FAdV-4) is recognized as a pathogen that causes hydropericardium syndrome. Irrespective of the pathway used by the virus to invade the chicken, the pathological characteristics of the disease include degeneration and necrosis ...
Mengyu Wang (385092), Yujuan Niu (13797340), Zhiyang Liu (4332328), Kaihui Chang (13797343), Ke Du (511486), Yonghe Ding (261003)   +5 more
core   +1 more source

A novel fiber-2-edited live attenuated vaccine candidate against the highly pathogenic serotype 4 fowl adenovirus

Veterinary Research, 2021
Recently, the outbreaks of hydropericardium-hepatitis syndrome (HHS) caused by the highly pathogenic fowl adenovirus serotype 4 (FAdV-4) have resulted in huge economic losses to the poultry industry globally.
Quan Xie, Shiya Cao, Wei Zhang, Weikang Wang, Luyuan Li, Qiuqi Kan, Hui Fu, Tuoyu Geng, Tuofan Li, Zhimin Wan, Wei Gao, Hongxia Shao, Aijian Qin, Jianqiang Ye   +13 more
doaj   +1 more source

Endosomal trafficking factor RAB5c acts as a host restriction factor against FAdV-4 propagation through interaction with ORF1B. [PDF]

Poult Sci
Gao H, Liu K, Ma M, Chang Q, Zhai S, Li J, Wang X, Yang X, Zhao J, Zhang X, Wang Z.   +10 more
europepmc   +2 more sources

Table_3_TMT-based quantitative proteomics analysis reveals the role of Notch signaling in FAdV-4-infected LMH cell.XLSX

, 2022
Fowl adenovirus serotype 4 (FAdV-4) is recognized as a pathogen that causes hydropericardium syndrome. Irrespective of the pathway used by the virus to invade the chicken, the pathological characteristics of the disease include degeneration and necrosis ...
Mengyu Wang (385092), Yujuan Niu (13797340), Zhiyang Liu (4332328), Kaihui Chang (13797343), Ke Du (511486), Yonghe Ding (261003)   +5 more
core   +1 more source